{"id":"W4405730724","doi":"10.1016/j.jtct.2024.12.016","title":"Early Engraftment and Immune Kinetics Following Allogeneic Transplant Using a Novel Reduced-Toxicity Transplant Strategy in Children/Adolescents with High-Risk Transfusion-Dependent Thalassemia: Early Results of the ThalFAbS Trial","year":2024,"lang":"en","type":"article","venue":"Transplantation and Cellular Therapy","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Children's Hospital of Eastern Ontario; London Health Sciences Centre; University of Toronto; SickKids Foundation; Hospital for Sick Children","funders":"Garron Family Cancer Centre; Thalassemia Foundation of Canada","keywords":"Thalassemia; Medicine; Pediatrics; Immune system; Intensive care medicine; Immunology; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009446839,0.0003652491,0.0007427372,0.000107759,0.0001459017,0.0006611805,0.0002184894,0.0003595907,0.0005805347],"category_scores_gemma":[0.0009949465,0.0001052556,0.0004798284,0.0001659565,0.0003541651,0.0004044541,0.000216755,0.001287494,0.0000812804],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003856582,"about_ca_system_score_gemma":0.0004464179,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003810844,"about_ca_topic_score_gemma":0.0006626321,"domain_scores_codex":[0.9997707,0.0001164622,0.000009982876,0.00002762566,0.00002680757,0.00004837808],"domain_scores_gemma":[0.9995746,0.0001393446,0.0001126428,0.00004621665,0.00001982642,0.0001074675],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.5382212,0.01499616,0.1842582,0.0003316651,0.002031061,0.0005603628,0.0006541887,0.005421132,0.03077711,0.0009996253,0.002440973,0.2193083],"study_design_scores_gemma":[0.1342406,0.4160346,0.4122484,0.0002376926,0.003374694,0.002027971,0.0004742597,0.004951844,0.01771449,0.001465398,0.007137405,0.00009266857],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991307,0.0004385996,0.0001061511,0.00005775425,0.00001011423,0.00002173751,0.00004253758,0.000003711041,0.0001887762],"genre_scores_gemma":[0.9989465,0.0003244219,0.0002083592,0.0001066542,0.00003006334,0.00003399742,0.0001589791,0.000004752449,0.000186313],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009446839,"threshold_uncertainty_score":0.004996061,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01544371709345254,"score_gpt":0.24277285338762,"score_spread":0.2273291362941674,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}