{"id":"W4405749371","doi":"10.1016/j.jval.2024.10.1283","title":"EPH155 The Impact of Adjuvant Alectinib in Reducing Recurrences and Recurrence-Related Treatment Costs in Resected Early-Stage ALK+ Non-Small Cell Lung Cancer Across Canada","year":2024,"lang":"en","type":"article","venue":"Value in Health","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Roche (Canada)","funders":"","keywords":"Alectinib; Medicine; Lung cancer; Stage (stratigraphy); Oncology; Adjuvant; Internal medicine; Crizotinib; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006137638,0.0002103663,0.000487505,0.0005322821,0.0009452831,0.001577693,0.0008523197,0.0003471313,0.002476734],"category_scores_gemma":[0.002793291,0.0001740683,0.0009149213,0.001387481,0.0004749212,0.0003504622,0.0006939807,0.000728913,0.0001241852],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.05011124,"about_ca_system_score_gemma":0.0864329,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.9909624,"about_ca_topic_score_gemma":0.9967146,"domain_scores_codex":[0.9990336,0.0001123438,0.00006282955,0.00008788535,0.0002413,0.0004620206],"domain_scores_gemma":[0.9979249,0.0001374317,0.00029054,0.00003382792,0.0008033886,0.0008099885],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003756159,0.000341032,0.7934753,0.0008410926,0.001664125,0.0004035818,0.0006193399,0.007561378,0.001657413,0.003114203,0.02933235,0.157234],"study_design_scores_gemma":[0.000439438,0.0003129901,0.9793732,0.0004471884,0.0008361262,0.0002155736,0.001675804,0.002627865,0.0005762133,0.0003300327,0.013118,0.00004755504],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9425021,0.01488507,0.0004003895,0.01634386,0.0001719186,0.000137879,0.009774251,0.00005260973,0.01573197],"genre_scores_gemma":[0.990755,0.003710198,0.0003944205,0.001009249,0.00002857709,0.00002269127,0.001688345,0.00001561463,0.002375893],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05011124,"threshold_uncertainty_score":0.3635842,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03071034357065988,"score_gpt":0.3951824215787885,"score_spread":0.3644720780081286,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}