{"id":"W4405756504","doi":"10.1021/acs.est.4c10931","title":"A Novel Organophosphate Ester, Tris(2,4-di<i>tert</i>-butylphenyl) Phosphate, Induced Reproductive Toxicity in Male Zebrafish at Environmentally Relevant Concentrations","year":2024,"lang":"en","type":"article","venue":"Environmental Science & Technology","topic":"Effects and risks of endocrine disrupting chemicals","field":"Environmental Science","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Carleton University","funders":"National Key Research and Development Program of China; China University of Geosciences; National Natural Science Foundation of China","keywords":"Zebrafish; Semen quality; Toxicity; Organophosphate; Sperm; Biology; Reproductive toxicity; Sperm motility; Spermatogenesis; Andrology; Motility; In vivo; Endocrine disruptor; Chemistry; Internal medicine; Endocrinology; Cell biology; Pesticide; Biochemistry; Gene; Ecology; Genetics; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007449085,0.0003960999,0.000173899,0.0001572139,0.0001200441,0.000146017,0.0001342655,0.0002884516,0.001131612],"category_scores_gemma":[0.0001009872,0.0001386853,0.0002426862,0.00008735168,0.0001743881,0.0001443357,0.0001364091,0.0002980826,0.0001144613],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002482284,"about_ca_system_score_gemma":0.000406537,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002448384,"about_ca_topic_score_gemma":0.004800563,"domain_scores_codex":[0.9999359,0.000005800984,0.000006214763,0.00001681247,0.00002183072,0.00001350028],"domain_scores_gemma":[0.9999491,0.000005891683,0.00001847662,0.000002942608,0.00001302953,0.00001061111],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008270382,0.000006146456,0.0002922978,0.00004374286,0.000005806807,0.0000729352,0.000007857809,0.00005880669,0.9987085,0.00002224623,0.00002459828,0.0006743181],"study_design_scores_gemma":[0.000009069618,0.0005604286,0.004032024,0.000007114998,0.00002299708,0.0001378988,0.00002713318,0.0002582439,0.9937617,0.00003168042,0.001146207,0.00000539289],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935284,0.001822728,0.002283187,0.0001386166,0.00004207144,0.00003969153,0.000511008,0.00005699631,0.001577388],"genre_scores_gemma":[0.9926842,0.001508729,0.001523256,0.00009239552,0.000006300608,0.0000410498,0.0003689194,0.000009547727,0.003765601],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002448384,"threshold_uncertainty_score":0.004868269,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006981214921465441,"score_gpt":0.2666535253904033,"score_spread":0.2596723104689379,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}