{"id":"W4405810128","doi":"10.3390/gels11010007","title":"Beyond Needles: Immunomodulatory Hydrogel-Guided Vaccine Delivery Systems","year":2024,"lang":"en","type":"review","venue":"Gels","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; University of British Columbia","funders":"Michael Smith Health Research BC; Canadian Bee Research Fund","keywords":"Immunogenicity; Self-healing hydrogels; Limiting; Immune system; Immunization; Nanotechnology; Medicine; Risk analysis (engineering); Immunology; Materials science; Engineering","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0007442397,0.001152174,0.003194602,0.0007906028,0.0003164145,0.0001323037,0.001049956,0.001618014,0.0007337074],"category_scores_gemma":[0.00005514166,0.000872625,0.001423455,0.000557331,0.0001700299,0.0001663533,0.0003462966,0.001486916,0.01723526],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004303604,"about_ca_system_score_gemma":0.0006869101,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000242189,"about_ca_topic_score_gemma":0.000001082593,"domain_scores_codex":[0.9956244,0.0007768997,0.001669983,0.0009037557,0.00009205763,0.0009329522],"domain_scores_gemma":[0.9974769,0.0004012101,0.0005393401,0.001437546,0.0001059626,0.00003905292],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001540923,0.0001768291,8.649607e-7,0.01809684,0.008248715,0.0001423394,0.0004941887,0.000002790332,0.003077333,0.00154283,0.07151359,0.8965496],"study_design_scores_gemma":[0.0006261886,0.0001597942,0.000001031361,0.01132705,0.002173315,0.001806175,0.0001129643,7.538888e-7,0.0002135448,0.00004897827,0.9826567,0.0008735278],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003882751,0.9875533,0.000009887861,0.00001171043,0.008618065,0.001332339,0.0002899446,0.0004122868,0.001384216],"genre_scores_gemma":[0.0003792835,0.9641956,0.000008256035,0.00008202218,0.0002373644,0.0001876778,0.0008767957,0.0002355878,0.03379738],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9111431,"threshold_uncertainty_score":0.9996781,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02984055261488476,"score_gpt":0.2933292104682113,"score_spread":0.2634886578533265,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}