{"id":"W4405835037","doi":"10.7554/elife.102986.1.sa0","title":"Author response: Acetylcholine modulates prefrontal outcome coding during threat learning under uncertainty","year":2024,"lang":"en","type":"peer-review","venue":"","topic":"Nicotinic Acetylcholine Receptors Study","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Acetylcholine; Coding (social sciences); Psychology; Neuroscience; Computer science; Cognitive psychology; Biology; Pharmacology; Mathematics; Statistics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00101866,0.0003126146,0.0002969778,0.0004071397,0.0004186913,0.0008564154,0.0006271591,0.001034103,0.04212442],"category_scores_gemma":[0.005681094,0.0001217715,0.0001302836,0.0002386416,0.0006326706,0.001140148,0.0008464556,0.0007627883,0.01146776],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004596083,"about_ca_system_score_gemma":0.0009170434,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005298877,"about_ca_topic_score_gemma":0.001625263,"domain_scores_codex":[0.99934,0.00008367302,0.00003973795,0.0001316713,0.000350245,0.00005461114],"domain_scores_gemma":[0.9969051,0.0004372261,0.0004183368,0.0002194546,0.001529797,0.0004900405],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001710538,0.0001740346,0.01002668,0.002241461,0.00008857231,0.003182963,0.001386388,0.001077579,0.5398433,0.01259246,0.1207214,0.3069547],"study_design_scores_gemma":[0.0002073007,0.0007926245,0.04844473,0.0005751004,0.0001267189,0.003663036,0.001782107,0.004598309,0.2417792,0.0113715,0.6865485,0.0001108286],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.5823296,0.0372778,0.03606768,0.06864271,0.03242164,0.0006995502,0.002758682,0.001970199,0.237832],"genre_scores_gemma":[0.6538458,0.0107926,0.007787058,0.002427063,0.003930246,0.0001268982,0.0008519485,0.0004410785,0.3197972],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.04212442,"threshold_uncertainty_score":0.1409202,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0380190744194138,"score_gpt":0.3595480024950854,"score_spread":0.3215289280756716,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}