{"id":"W4405843580","doi":"10.1038/s41598-024-81276-3","title":"Mesenchymal stromal cells reduce inflammation and improve lung function in a mouse model of cystic fibrosis lung disease","year":2024,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Mesenchymal stem cell research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Queen's University; Medical Research Council; Bundesministerium für Bildung und Forschung; Deutsche Forschungsgemeinschaft; Department for the Economy","keywords":"Mesenchymal stem cell; Lung; Inflammation; Medicine; Fibrosis; Bone marrow; Bronchoalveolar lavage; Pathology; Stromal cell; Chemokine; Cystic fibrosis; Osteopontin; Cancer research; Immunology; Internal medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002768499,0.0005804559,0.0006532547,0.000636264,0.0001502169,0.0002322723,0.0002016734,0.0006351779,0.001191055],"category_scores_gemma":[0.0001309482,0.0001291345,0.0003298554,0.0001859733,0.0003036055,0.0002694154,0.0001728279,0.001048581,0.0002273926],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001688982,"about_ca_system_score_gemma":0.0002538268,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004485855,"about_ca_topic_score_gemma":0.0009106155,"domain_scores_codex":[0.9997526,0.00005050251,0.00002897572,0.00003264545,0.00009142486,0.00004385793],"domain_scores_gemma":[0.9998203,0.00001773603,0.00005428965,0.00001290564,0.00001930124,0.00007555953],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008146276,0.0005211678,0.0002376704,0.0001011481,0.00002023806,0.00006968218,0.000026121,0.0001745233,0.992869,0.00009327112,0.0001377483,0.004934739],"study_design_scores_gemma":[0.000392453,0.008890961,0.005741728,0.00005487815,0.0001147575,0.0003458021,0.00009518444,0.002057997,0.9766386,0.0001822132,0.005469743,0.00001562034],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9877154,0.004951245,0.004128186,0.0006592786,0.0002419182,0.0001318899,0.0005024223,0.0002568749,0.001412652],"genre_scores_gemma":[0.9860386,0.003732598,0.004148359,0.0002968282,0.0000629087,0.0001941781,0.0006831874,0.00004443355,0.004798844],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001191055,"threshold_uncertainty_score":0.003984451,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01639227021081518,"score_gpt":0.2830682196445605,"score_spread":0.2666759494337453,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}