{"id":"W4405852876","doi":"10.1111/jnc.16292","title":"Plasticity of Mouse Dorsal Root Ganglion Neurons by Innate Immune Activation Is Influenced by Electrophysiological Activity","year":2024,"lang":"en","type":"article","venue":"Journal of Neurochemistry","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; International Collaboration On Repair Discoveries; Women and Children’s Health Research Institute; University of Alberta","funders":"Canadian Institutes of Health Research; University of Alberta; Natural Sciences and Engineering Research Council of Canada; Multiple Sclerosis Society of Canada; European Genomic Institute for Diabetes","keywords":"Dorsal root ganglion; Neuroscience; Electrophysiology; Inflammation; Immune system; Blockade; Premovement neuronal activity; Sensory system; Biology; Neuroplasticity; Multiple sclerosis; Receptor; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002398156,0.000306927,0.0002361986,0.0003512109,0.0001073867,0.0003251942,0.0002141067,0.000284996,0.001059294],"category_scores_gemma":[0.0001628069,0.0001521628,0.0003132883,0.0001547339,0.0003447899,0.0002376412,0.0001973614,0.0008560932,0.0002443199],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002208134,"about_ca_system_score_gemma":0.0001511233,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003497932,"about_ca_topic_score_gemma":0.0009219197,"domain_scores_codex":[0.999744,0.00003695054,0.00003485788,0.00005995223,0.00006101027,0.00006325053],"domain_scores_gemma":[0.9998466,0.00003680559,0.00004352171,0.0000219733,0.00001560487,0.00003545951],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008078797,0.00001813402,0.0001146796,0.00001376014,0.000002044679,0.0000206869,0.00001146586,0.00002379962,0.9992305,0.00002743215,0.000004767284,0.0004519604],"study_design_scores_gemma":[0.000017802,0.000568562,0.008260044,0.00001163682,0.00001599997,0.0001179836,0.00004780063,0.0006058351,0.9898886,0.00007829691,0.0003819562,0.000005428226],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957396,0.0008538643,0.002204416,0.00005330073,0.00002515355,0.00002079843,0.0002585423,0.00004764197,0.0007966724],"genre_scores_gemma":[0.9936246,0.001019901,0.002967258,0.00004689692,0.000008645895,0.00008940986,0.0002585907,0.00002132401,0.001963452],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001059294,"threshold_uncertainty_score":0.003543675,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008037246485544748,"score_gpt":0.2581659410238915,"score_spread":0.2501286945383467,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}