{"id":"W4405893976","doi":"10.1038/s41467-024-55050-y","title":"A high-protein diet-responsive gut hormone regulates behavioral and metabolic optimization in Drosophila melanogaster","year":2024,"lang":"en","type":"article","venue":"Nature Communications","topic":"Aquaculture Nutrition and Growth","field":"Agricultural and Biological Sciences","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics; Core Research for Evolutional Science and Technology; Life Science Center for Survival Dynamics Tsukuba Advanced Research Alliance; Japan Society for the Promotion of Science; Ministry of Education, Culture, Sports, Science and Technology; University of Tsukuba; Japan Agency for Medical Research and Development","keywords":"Drosophila melanogaster; Drosophila (subgenus); Hormone; Feeding behavior; Biology; Cell biology; Bioinformatics; Genetics; Endocrinology; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005234399,0.000219739,0.0001112643,0.0002622178,0.0001667485,0.0002174994,0.0001758353,0.0001673498,0.0009039789],"category_scores_gemma":[0.00005952921,0.0001353121,0.000196039,0.0000987146,0.0002027023,0.0001281837,0.0002203942,0.0003592594,0.0002372715],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005124723,"about_ca_system_score_gemma":0.0001936486,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002515492,"about_ca_topic_score_gemma":0.005639595,"domain_scores_codex":[0.9999529,0.000006001015,0.00000416614,0.00001640784,0.00001210816,0.000008369548],"domain_scores_gemma":[0.99994,0.000008047329,0.00001889411,0.000006298232,0.000007266511,0.00001942139],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003963385,0.000005368936,0.0006062259,0.00002040137,0.00000338216,0.00007233246,0.0000161878,0.00006584099,0.9979377,0.0000698678,0.00005582584,0.00110728],"study_design_scores_gemma":[0.00004670434,0.0001835735,0.1155115,0.00002936191,0.00003823056,0.0005301487,0.0002248812,0.003895227,0.8708969,0.0001893491,0.008426005,0.00002820951],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.991121,0.001337436,0.003201982,0.0001395121,0.00002825545,0.00002426272,0.001462611,0.0001041953,0.002580714],"genre_scores_gemma":[0.9889711,0.0008613302,0.003129975,0.0001418853,0.000006522099,0.00004561645,0.0009689304,0.00005987124,0.005814769],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002515492,"threshold_uncertainty_score":0.005001724,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01987031566045729,"score_gpt":0.2693738472168783,"score_spread":0.249503531556421,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}