{"id":"W4405944467","doi":"10.1128/aem.01971-24","title":"RecA deletion disrupts protein homeostasis, leading to deamidation, oxidation, and impaired glycolysis in <i>Cronobacter sakazakii</i>","year":2024,"lang":"en","type":"article","venue":"Applied and Environmental Microbiology","topic":"Enterobacteriaceae and Cronobacter Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"Deamidation; Cronobacter sakazakii; Glycolysis; Biology; Homeostasis; Microbiology; Chemistry; Biochemistry; Cell biology; Metabolism; Bacteria; Genetics; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001256361,0.0005299066,0.00029169,0.0001735167,0.00012852,0.0003016962,0.0003081259,0.0003690779,0.0009332662],"category_scores_gemma":[0.0001984421,0.0001422238,0.0003568876,0.0001689657,0.0001848122,0.0001409272,0.000263872,0.0004777118,0.0005391018],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002620299,"about_ca_system_score_gemma":0.0002021503,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00233844,"about_ca_topic_score_gemma":0.001630972,"domain_scores_codex":[0.9997422,0.00003601258,0.00003636329,0.00006362618,0.00007123809,0.00005055345],"domain_scores_gemma":[0.9997821,0.00002316016,0.0001048858,0.00002458108,0.00003126024,0.00003406093],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008303455,0.00002165553,0.0003141492,0.00002841773,0.000005418422,0.00005102898,0.0000075354,0.00002881694,0.9987418,0.00001351447,0.00003394277,0.0006706992],"study_design_scores_gemma":[0.00001004753,0.0004164944,0.01880935,0.00001912863,0.00002241775,0.0006285421,0.0001042222,0.0008155256,0.9760291,0.00002439335,0.003108187,0.0000125322],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935964,0.0009395287,0.002900739,0.0001500938,0.00005125591,0.00003915106,0.001126872,0.0001829159,0.001013004],"genre_scores_gemma":[0.9919751,0.0005228535,0.003181288,0.00007183749,0.000008213348,0.00002851207,0.001925713,0.00006302034,0.002223544],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00233844,"threshold_uncertainty_score":0.004649699,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004149280983311735,"score_gpt":0.216196512630777,"score_spread":0.2120472316474652,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}