{"id":"W4405945006","doi":"10.3390/vaccines13010019","title":"Immunobridging Trials: An Important Tool to Protect Vulnerable and Immunocompromised Patients Against Evolving Pathogens","year":2024,"lang":"en","type":"article","venue":"Vaccines","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Paul's Hospital; University of British Columbia","funders":"","keywords":"Safeguarding; Intensive care medicine; Medicine; Context (archaeology); Coronavirus disease 2019 (COVID-19); Clinical trial; Infectious disease (medical specialty); Disease; Biology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.1228408,0.000869637,0.001899486,0.001737791,0.001350217,0.006457628,0.001446522,0.004784851,0.006316926],"category_scores_gemma":[0.1332977,0.0004884399,0.0009413133,0.001584705,0.004453863,0.008275851,0.003232595,0.006897002,0.001269977],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001546774,"about_ca_system_score_gemma":0.006009375,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002299908,"about_ca_topic_score_gemma":0.0005429902,"domain_scores_codex":[0.9127509,0.07738636,0.003007247,0.001817335,0.004480165,0.0005579914],"domain_scores_gemma":[0.8417355,0.1092227,0.0228247,0.01062681,0.008481442,0.007108891],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.009574876,0.00113201,0.006401189,0.008747553,0.001338345,0.000363466,0.001469432,0.001472156,0.006364286,0.08342604,0.0460512,0.8336596],"study_design_scores_gemma":[0.01299887,0.03663641,0.013834,0.02656515,0.002038612,0.001498282,0.00195633,0.003576868,0.01041943,0.2185245,0.6715481,0.0004033982],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.06715699,0.2764045,0.1406202,0.4150821,0.03100423,0.0109237,0.0009274152,0.00100387,0.05687704],"genre_scores_gemma":[0.4285394,0.1361099,0.2146165,0.1626191,0.03409432,0.01397212,0.0005469029,0.0003441545,0.009157687],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.1228408,"threshold_uncertainty_score":0.6496519,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04125525598092687,"score_gpt":0.348840272989713,"score_spread":0.3075850170087861,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}