{"id":"W4405965330","doi":"10.3390/cells14010034","title":"Bi-Hormonal Endocrine Cell Presence Within the Islets of Langerhans of the Human Pancreas Throughout Life","year":2025,"lang":"en","type":"article","venue":"Cells","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"St Joseph's Health Care; McMaster University; Lawson Health Research Institute; Western University","funders":"Canadian Institutes of Health Research; Lawson Foundation; Lawson Health Research Institute","keywords":"Glucagon; Somatostatin; Endocrinology; Internal medicine; Hormone; Islet; Pancreas; Enteroendocrine cell; Insulin; Delta cell; Biology; Pancreatic polypeptide; Endocrine system; Pancreatic hormone; Medicine; Insulin resistance","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002597066,0.0001413387,0.0001637805,0.0006115134,0.0001880533,0.0005336676,0.0000863672,0.0001290738,0.001642525],"category_scores_gemma":[0.0004257251,0.0001344463,0.000132172,0.0003958462,0.0001440839,0.0002955449,0.0002802398,0.0002164796,0.0003828959],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009319853,"about_ca_system_score_gemma":0.0001023639,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005074525,"about_ca_topic_score_gemma":0.0005904979,"domain_scores_codex":[0.9998616,0.0000175852,0.00001257896,0.00004528515,0.00004229051,0.00002050861],"domain_scores_gemma":[0.9996216,0.00005954605,0.0001059626,0.00004071068,0.0001061136,0.0000660993],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.000647263,0.00002706754,0.2476416,0.0001460735,0.00006461606,0.0008473455,0.0006909102,0.00008604073,0.710465,0.0001950557,0.0002177643,0.03897128],"study_design_scores_gemma":[0.000003732302,0.0002049145,0.9606625,0.00002062736,0.00005750256,0.003660986,0.0003200184,0.0001737696,0.03062754,0.0001058523,0.004149525,0.00001297385],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920951,0.004298638,0.00146216,0.00002509574,0.00001201547,0.000007358837,0.0002488918,0.00002455392,0.001826209],"genre_scores_gemma":[0.9947633,0.001919153,0.001175891,0.00002546468,0.00001545722,0.00001434615,0.0003306041,0.00001062365,0.001745161],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001642525,"threshold_uncertainty_score":0.005494773,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01482366703590668,"score_gpt":0.2703210428935969,"score_spread":0.2554973758576902,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}