{"id":"W4405971274","doi":"10.1093/jb/mvae082","title":"GPLD1+ cancer stem cells contribute to chemotherapy resistance and tumour relapse in intestinal cancer","year":2024,"lang":"en","type":"article","venue":"The Journal of Biochemistry","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics; Japan Society for the Promotion of Science; Research Organization of Information and Systems","keywords":"Cancer; Cancer stem cell; Medicine; Oncology; Chemotherapy; Cancer chemotherapy; Stem cell; Internal medicine; Cancer research; Biology; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005390074,0.0001354789,0.0003013035,0.00006014272,0.00002809839,0.00002833903,0.0001180362,0.00005137745,0.0001163178],"category_scores_gemma":[0.00002545035,0.00008761128,0.00007397487,0.00026263,0.0000750769,0.0000361926,0.00002709866,0.000398477,0.000002167997],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002730233,"about_ca_system_score_gemma":0.0004006658,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001301012,"about_ca_topic_score_gemma":0.00009038651,"domain_scores_codex":[0.9990531,0.00002403023,0.0003476775,0.0001412758,0.000236073,0.0001977934],"domain_scores_gemma":[0.9993362,0.0001043582,0.0001212717,0.0001422944,0.0001265904,0.0001692471],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001228696,0.00003454879,0.0009327685,0.000457627,0.0001046636,0.0001608026,0.0005473249,0.00001829299,0.9615377,0.000003841029,0.0247627,0.01021099],"study_design_scores_gemma":[0.001098863,0.0000793712,0.001069124,0.002915123,0.0001783386,0.0002596219,0.0003106632,0.00001647761,0.962467,0.00002483243,0.03147152,0.0001090218],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9230641,0.06213002,0.00006376667,0.01409162,0.0002822708,0.0001235721,0.00004005991,0.000009286529,0.000195367],"genre_scores_gemma":[0.9820018,0.01100708,0.0001901435,0.000809465,0.0005056982,0.000007831313,4.666011e-7,0.00002184134,0.00545562],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05893782,"threshold_uncertainty_score":0.3572684,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01179994433663649,"score_gpt":0.2856318518409559,"score_spread":0.2738319075043193,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}