{"id":"W4405971274","doi":"10.1093/jb/mvae082","title":"GPLD1+ cancer stem cells contribute to chemotherapy resistance and tumour relapse in intestinal cancer","year":2024,"lang":"en","type":"article","venue":"The Journal of Biochemistry","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics; Japan Society for the Promotion of Science; Research Organization of Information and Systems","keywords":"Cancer; Cancer stem cell; Medicine; Oncology; Chemotherapy; Cancer chemotherapy; Stem cell; Internal medicine; Cancer research; Biology; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001311553,0.0001746869,0.0002892108,0.0004232728,0.0001663229,0.0003294481,0.0001410827,0.0003361576,0.002129342],"category_scores_gemma":[0.0002407863,0.0001206754,0.000153082,0.0002091958,0.0002413996,0.000150979,0.0002577664,0.000531178,0.0002340662],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002746204,"about_ca_system_score_gemma":0.0001591245,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003801501,"about_ca_topic_score_gemma":0.0004150542,"domain_scores_codex":[0.999929,0.0000154139,0.000005550618,0.00001309167,0.00001812146,0.00001882065],"domain_scores_gemma":[0.9998498,0.00002332296,0.00006109441,0.00001562252,0.00001034029,0.00003972608],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001999385,0.00033926,0.05616552,0.0002425018,0.00005161147,0.001825757,0.0002590086,0.0007854686,0.8988413,0.001383725,0.0008687098,0.03723769],"study_design_scores_gemma":[0.00033195,0.003102543,0.531224,0.00006759885,0.0003066694,0.01298331,0.0006699892,0.01547714,0.4105511,0.003129314,0.02210886,0.00004758872],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970462,0.001370325,0.000625044,0.0001550519,0.000006150005,0.00002456396,0.0001124739,0.00006383406,0.0005964752],"genre_scores_gemma":[0.9983857,0.0003992967,0.000185664,0.0000348682,0.0000057037,0.00001313832,0.0001270936,0.000006121669,0.0008424035],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002129342,"threshold_uncertainty_score":0.007123351,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01179994433663649,"score_gpt":0.2856318518409559,"score_spread":0.2738319075043193,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}