{"id":"W4405973479","doi":"10.7759/cureus.76762","title":"A Comparative, Multicenter, Prospective, Randomized Study to Evaluate the Efficacy, Safety, and Delay of Relapse of Ceramide-Based Post-biotic Moisturizer Versus Paraffin-Based Moisturizer in Mild to Moderate Atopic Dermatitis","year":2025,"lang":"en","type":"article","venue":"Cureus","topic":"Dermatology and Skin Diseases","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"SKiN Health","funders":"","keywords":"Moisturizer; Medicine; Atopic dermatitis; Dermatology; Randomized controlled trial; Multicenter study; Internal medicine; Food science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003430755,0.00114162,0.003693688,0.0004213455,0.0006093296,0.000778951,0.001065362,0.001885304,0.005118957],"category_scores_gemma":[0.003265867,0.0006908156,0.001561682,0.0004726694,0.001386403,0.001039591,0.0004016301,0.001940779,0.0007854523],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006420371,"about_ca_system_score_gemma":0.001351948,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005284711,"about_ca_topic_score_gemma":0.0008439083,"domain_scores_codex":[0.9981928,0.001020463,0.0001550913,0.0002935872,0.0001613598,0.0001767562],"domain_scores_gemma":[0.9971446,0.0008541552,0.0007248834,0.0002518671,0.0002053408,0.0008192061],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9760617,0.01482903,0.001924152,0.0001673206,0.0004354639,0.00003436023,0.00003933387,0.00006379789,0.00189129,0.00003983428,0.0001108999,0.004402875],"study_design_scores_gemma":[0.6399743,0.3529297,0.005934014,0.00001660596,0.000337734,0.00004839517,0.00003284448,0.00017575,0.0002840685,0.00005061656,0.0002050446,0.00001098645],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964848,0.001166371,0.0001849514,0.0001042157,0.0001834813,0.001367801,0.0001630479,0.00001466222,0.0003305464],"genre_scores_gemma":[0.9939738,0.0008205152,0.000848529,0.0004365008,0.0003815806,0.002474093,0.0003453469,0.000006437678,0.0007132452],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005118957,"threshold_uncertainty_score":0.01814377,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02033873857168431,"score_gpt":0.3249329618428242,"score_spread":0.3045942232711399,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}