{"id":"W4405980926","doi":"10.1093/geroni/igae098.4249","title":"PICOLINIC ACID, A CATABOLITE OF TRYPTOPHAN, HAS AN ANABOLIC EFFECT ON MYOBLASTS AND INCREASES MOBILITY IN C. ELEGANS","year":2024,"lang":"en","type":"article","venue":"Innovation in Aging","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Catabolite repression; Picolinic acid; Tryptophan; Anabolism; Chemistry; Cell biology; Biochemistry; Biology; Amino acid","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006881857,0.000414825,0.0002812275,0.0003762078,0.0002676106,0.0002138963,0.0002823685,0.0003146536,0.001005591],"category_scores_gemma":[0.00007386829,0.0001735266,0.0004171931,0.0001541507,0.0001997939,0.000149492,0.0003005874,0.0005551949,0.0002326318],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003608435,"about_ca_system_score_gemma":0.0002206684,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002071492,"about_ca_topic_score_gemma":0.00348287,"domain_scores_codex":[0.9998894,0.00000803561,0.00001315363,0.00003042765,0.00003302452,0.00002596424],"domain_scores_gemma":[0.9998707,0.00001368637,0.00004054891,0.00001100439,0.00002158817,0.00004258752],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008258272,0.00001847065,0.0002067081,0.00004123821,0.000003454842,0.00003739523,0.00000727704,0.00002457702,0.9991207,0.00001728733,0.00003126801,0.0004091656],"study_design_scores_gemma":[0.00003451893,0.0007703959,0.02418747,0.00003084205,0.00002996666,0.0002360674,0.0000799913,0.0009544449,0.9706239,0.00004619905,0.002989555,0.00001661749],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928666,0.00161382,0.001542488,0.0001571176,0.00005544568,0.00004730794,0.001718165,0.0001435033,0.001855525],"genre_scores_gemma":[0.9885131,0.0008852183,0.003703097,0.000107697,0.000009266158,0.0001009427,0.001468168,0.00003747487,0.005174912],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002071492,"threshold_uncertainty_score":0.00411886,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01617633745840983,"score_gpt":0.2979222231122604,"score_spread":0.2817458856538506,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}