{"id":"W4405983085","doi":"10.1038/s41585-024-00974-9","title":"Antibiotic therapy for treating overactive bladder is not supported by clinical evidence","year":2025,"lang":"en","type":"review","venue":"Nature Reviews Urology","topic":"Urinary Bladder and Prostate Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Medicine; Overactive bladder; Intensive care medicine; Antibiotics; Adverse effect; Oxybutynin; Pharmacotherapy; Anticholinergic; Antibiotic therapy; Regimen; Internal medicine; Alternative medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.003133804,0.0008509537,0.006125105,0.0003593844,0.0001459415,0.00003658761,0.0005157414,0.002869067,0.000626457],"category_scores_gemma":[0.004909511,0.0005554623,0.002318262,0.0007774214,0.0002055507,0.0001117656,0.0001471506,0.004638769,0.0001572627],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001141843,"about_ca_system_score_gemma":0.00169621,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000712185,"about_ca_topic_score_gemma":0.000001354287,"domain_scores_codex":[0.9931638,0.002040098,0.002046503,0.001512671,0.0003935568,0.000843359],"domain_scores_gemma":[0.9894519,0.007832682,0.0009093034,0.001159976,0.0003604501,0.0002856476],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004522383,0.0002697774,0.00005622151,0.02935291,0.0008149149,0.0000518976,0.00002120373,2.404015e-9,0.00000420417,0.00001279032,0.1321472,0.8368166],"study_design_scores_gemma":[0.001062348,0.002480864,0.00002671264,0.01564955,0.003091031,0.0002600393,0.000001940602,0.000004348709,0.0000161313,0.00001682812,0.9770129,0.000377272],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000004702262,0.9863075,0.00004681436,0.002064015,0.0005641166,0.009422484,0.0003504893,0.00005374154,0.001186142],"genre_scores_gemma":[0.00001547333,0.9849625,0.0004037724,0.007176014,0.0006980638,0.0004100355,0.0008103574,0.00009433466,0.005429467],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8448657,"threshold_uncertainty_score":0.9996897,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1534266030110184,"score_gpt":0.5286888300173307,"score_spread":0.3752622270063123,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}