{"id":"W4405999050","doi":"10.1101/2024.12.18.628357","title":"A Locus Control Region Generates Distinct Active Placental Lactogen And Inactive Growth Hormone Gene Domains In Term Placenta That Are Disrupted With Obesity","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Birth, Development, and Health","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"Placental lactogen; Placenta; Endocrinology; Locus (genetics); Internal medicine; Biology; Hormone; Gene; Growth hormone; Genetics; Medicine; Pregnancy; Fetus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009435359,0.0002724472,0.0001393101,0.0002911193,0.0001362587,0.0002120994,0.0001815359,0.0002377969,0.002643927],"category_scores_gemma":[0.0001347439,0.0002297616,0.0003411521,0.0001579043,0.0003538298,0.00007274423,0.0002578695,0.0005216532,0.0004311409],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002383728,"about_ca_system_score_gemma":0.0001591988,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00110194,"about_ca_topic_score_gemma":0.001866422,"domain_scores_codex":[0.9998679,0.0000149322,0.00001095422,0.00004473997,0.00003241897,0.0000290268],"domain_scores_gemma":[0.9998199,0.0000242978,0.00006931323,0.00002034107,0.000007730117,0.00005838769],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001562848,0.00001071067,0.0004227773,0.00001585308,0.000005942217,0.0001485583,0.0000205756,0.00002004678,0.9983572,0.00008591139,0.00002570304,0.0007304171],"study_design_scores_gemma":[0.0001158743,0.0004631974,0.07937793,0.00002983356,0.00008831529,0.004419734,0.0001594648,0.001938307,0.9046761,0.0002705537,0.0084392,0.00002149048],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936295,0.0004251994,0.004423011,0.00005138864,0.00002989927,0.00002020682,0.0006371969,0.0001184171,0.0006651609],"genre_scores_gemma":[0.9946626,0.000225966,0.001520722,0.00005418644,0.000004420117,0.00002793997,0.0008788319,0.00007896234,0.002546323],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002643927,"threshold_uncertainty_score":0.008844793,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0142143684271754,"score_gpt":0.2288183911595525,"score_spread":0.2146040227323771,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}