{"id":"W4406030350","doi":"10.1002/cac2.12650","title":"A strong internal promoter drives massive expression of YEATS‐domain devoid <i>MLLT3</i> transcripts in HSC and most lethal AML","year":2025,"lang":"en","type":"article","venue":"Cancer Communications","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institut National Du Cancer; Association Laurette Fugain; Ministère de la Santé; Fondation ARC pour la Recherche sur le Cancer; Fondation de France; Institut National de la Santé et de la Recherche Médicale; Agence Nationale de la Recherche","keywords":"RNA polymerase II; Transcription factor; Transactivation; Molecular biology; Cell biology; Transcription (linguistics); Biology; Chemistry; Promoter; Gene expression; Genetics; Gene","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001685487,0.0001136473,0.0002570255,0.0002151512,0.00008651872,0.00001529313,0.0004742939,0.00008667965,0.00005867145],"category_scores_gemma":[0.00006725472,0.0001025568,0.00004449436,0.0003442646,0.0004036433,0.0001029541,0.0003352213,0.0005334118,0.000001775249],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003017428,"about_ca_system_score_gemma":0.000482024,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006159957,"about_ca_topic_score_gemma":0.0007407632,"domain_scores_codex":[0.998997,0.0001700852,0.0002981997,0.0001910872,0.0001470862,0.0001964809],"domain_scores_gemma":[0.9986604,0.0001481513,0.00006766067,0.0009212754,0.0001256058,0.00007686263],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006032182,0.0005168442,0.09641122,0.0004870059,0.0001868069,0.00002413077,0.0111624,0.00002388868,0.8568508,0.004388277,0.005709969,0.02363541],"study_design_scores_gemma":[0.02624825,0.0007915847,0.3927009,0.0152675,0.0004508959,0.00008436997,0.01974658,0.008255318,0.4384224,0.004993828,0.09201188,0.001026434],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9560666,0.006142591,0.00222137,0.01751391,0.00006703017,0.0009132651,0.0000811684,0.0000326674,0.01696141],"genre_scores_gemma":[0.9914172,0.00147171,0.005630355,0.0002222872,0.00001961084,0.0002486758,0.00003429069,0.00001470802,0.0009411442],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4184284,"threshold_uncertainty_score":0.4182145,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03057785634176597,"score_gpt":0.3543113829083722,"score_spread":0.3237335265666063,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}