{"id":"W4406030350","doi":"10.1002/cac2.12650","title":"A strong internal promoter drives massive expression of YEATS‐domain devoid <i>MLLT3</i> transcripts in HSC and most lethal AML","year":2025,"lang":"en","type":"article","venue":"Cancer Communications","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institut National Du Cancer; Association Laurette Fugain; Ministère de la Santé; Fondation ARC pour la Recherche sur le Cancer; Fondation de France; Institut National de la Santé et de la Recherche Médicale; Agence Nationale de la Recherche","keywords":"RNA polymerase II; Transcription factor; Transactivation; Molecular biology; Cell biology; Transcription (linguistics); Biology; Chemistry; Promoter; Gene expression; Genetics; Gene","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000188683,0.0004357454,0.0002935536,0.0003792271,0.000269199,0.0005450306,0.0003268933,0.0003867703,0.003147077],"category_scores_gemma":[0.0001689916,0.0002411468,0.0002829223,0.0003261048,0.0006452866,0.0001486589,0.0004485212,0.001124294,0.001465383],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008038794,"about_ca_system_score_gemma":0.0002382012,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000796752,"about_ca_topic_score_gemma":0.001444822,"domain_scores_codex":[0.9997261,0.00003588998,0.0000352781,0.00005439056,0.00008836191,0.00005999245],"domain_scores_gemma":[0.9997239,0.00004643068,0.00008406387,0.00003152599,0.00001244138,0.0001017332],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007829742,0.00002547835,0.000151346,0.00001830744,0.000003904926,0.0001171917,0.00002431878,0.0001238902,0.9980414,0.0004042352,0.00019193,0.0008195777],"study_design_scores_gemma":[0.00006252156,0.0001932694,0.005258062,0.00001504455,0.00002233412,0.00103668,0.00006291537,0.00242509,0.9805697,0.0001890697,0.01015252,0.00001282007],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9805796,0.001073534,0.008455404,0.0003730187,0.0001141956,0.0001778837,0.003346597,0.001139964,0.004739785],"genre_scores_gemma":[0.9921193,0.0002370841,0.00220548,0.00008995496,0.00003172745,0.0000536053,0.00142658,0.0001912604,0.003645002],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003147077,"threshold_uncertainty_score":0.01052797,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03057785634176597,"score_gpt":0.3543113829083722,"score_spread":0.3237335265666063,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}