{"id":"W4406041292","doi":"10.1111/trf.18116","title":"Hemoglobin‐based oxygen carriers: Biochemical, biophysical differences, and safety","year":2025,"lang":"en","type":"article","venue":"Transfusion","topic":"Hemoglobin structure and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Hemoglobin; Oxygen; Blood preservation; Medicine; Chemistry; Biochemistry; Physiology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005164812,0.0001473557,0.0001399959,0.00003745706,0.0001138934,0.00001821249,0.0000888514,0.0001974909,0.0000300556],"category_scores_gemma":[0.00001639558,0.0001262785,0.00007073152,0.0001319508,0.0001069768,0.000002690679,0.000030457,0.00008879536,0.000002355595],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001258542,"about_ca_system_score_gemma":0.0000623085,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003687971,"about_ca_topic_score_gemma":0.00001185701,"domain_scores_codex":[0.9992186,0.00003101829,0.000143196,0.0003543387,0.00008565824,0.0001672175],"domain_scores_gemma":[0.9996471,0.00001067824,0.00001817923,0.0002169858,0.00003553949,0.00007153424],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002880146,0.00002988251,0.002086845,0.00003556009,0.00002292142,7.872411e-7,0.00001788712,0.000002683139,0.9887682,0.0001209221,0.001725557,0.006900706],"study_design_scores_gemma":[0.001884822,0.0002732269,0.03116966,0.00005994665,0.00007081443,0.000005010694,0.00006538975,0.0003260192,0.9142306,0.0002483757,0.05135089,0.0003152107],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9855124,0.0003567539,0.01143835,0.0004736111,0.0001852278,0.0001789196,0.00002689634,0.00002490679,0.00180297],"genre_scores_gemma":[0.9982869,0.0002749824,0.0003748866,0.0005435094,0.0001038729,0.000009819851,0.0001009264,0.000008679441,0.0002963982],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07453761,"threshold_uncertainty_score":0.5149487,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005409829414439073,"score_gpt":0.2226774834774132,"score_spread":0.2172676540629742,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}