{"id":"W4406051178","doi":"10.1002/alz.085169","title":"Regularity of blood transfusion influences the severity of systemic iron burden, cognitive decline, and gut dysbiosis in thalassemia patients","year":2024,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Hemoglobinopathies and Related Disorders","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Dysbiosis; Neurocognitive; Thalassemia; Internal medicine; Montreal Cognitive Assessment; Blood transfusion; Hemoglobin; Gastroenterology; Ferritin; Gut flora; Physiology; Cognition; Immunology; Disease; Psychiatry; Dementia","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003253257,0.0002518491,0.00022029,0.0004709378,0.0003192005,0.0004251548,0.0001275667,0.0003190122,0.001554398],"category_scores_gemma":[0.001425882,0.0001394876,0.000242999,0.0004134992,0.0002065603,0.0001971275,0.0002095951,0.0003428267,0.0001697034],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001625712,"about_ca_system_score_gemma":0.0001191875,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002552966,"about_ca_topic_score_gemma":0.003030346,"domain_scores_codex":[0.9998409,0.00003854141,0.00002261683,0.00004134093,0.00002834411,0.00002825526],"domain_scores_gemma":[0.9992245,0.0001324368,0.0003446658,0.00003830146,0.0000809178,0.0001791645],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0006362007,0.0000978094,0.9954716,0.000009960634,0.0000524495,0.0001408685,0.0001800214,0.00003711109,0.001291164,0.00000960566,0.00008181632,0.001991557],"study_design_scores_gemma":[0.000004375297,0.000161809,0.9992321,0.000004231165,0.00002515404,0.0001982551,0.0001023937,0.0001096304,0.00009222385,0.0000132006,0.0000540898,0.000002526257],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9996274,0.000101741,0.00001785593,0.00001324605,0.000002174366,0.000002361229,0.00004089851,0.000001250304,0.0001931877],"genre_scores_gemma":[0.9998083,0.00002896139,0.00002686285,0.000008006832,0.000002921557,0.000001925455,0.00004355127,6.034363e-7,0.00007893654],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002552966,"threshold_uncertainty_score":0.005199969,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009205644238973442,"score_gpt":0.251634902292996,"score_spread":0.2424292580540225,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}