{"id":"W4406085059","doi":"10.1111/all.16466","title":"Skin Tape Stripping Reveals Distinct Biomarker Profiles in Chronic Hand Eczema of Patients With and Without Comorbid Atopic Dermatitis","year":2025,"lang":"en","type":"article","venue":"Allergy","topic":"Dermatology and Skin Diseases","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Innovaderm (Canada)","funders":"Division of Chemistry; LEO Fondet","keywords":"Atopic dermatitis; Medicine; Eczema Area and Severity Index; Immunology; CCL17; Immune dysregulation; Atopy; Biomarker; Allergy; Filaggrin; SCORAD; Chemokine; Immune system; Biology; Dermatology Life Quality Index; Psoriasis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000419807,0.000112351,0.0003055584,0.0001218735,0.00004669883,0.000008517939,0.00005120689,0.0000663623,0.00007233518],"category_scores_gemma":[0.00005702603,0.00008789617,0.00002534213,0.0001574935,0.0001904801,0.00005351551,0.00004327467,0.00006573406,0.000001567824],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000357555,"about_ca_system_score_gemma":0.000111837,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006252966,"about_ca_topic_score_gemma":0.0002529967,"domain_scores_codex":[0.9992751,0.00005321218,0.0002419808,0.000171092,0.0001006814,0.0001579359],"domain_scores_gemma":[0.9995922,0.00005581725,0.00007680227,0.0001692964,0.00005609435,0.00004983382],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00009970806,0.0001154353,0.9939618,0.0004204633,0.0001520923,0.00002160817,0.00007581322,9.948159e-7,0.00005657369,0.0001257653,0.002037287,0.002932491],"study_design_scores_gemma":[0.00322307,0.0000611831,0.9927413,0.0008131801,0.00004083676,0.000008425716,0.00002486743,0.0001050395,0.0005987621,0.0001238995,0.002178525,0.00008084349],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957061,0.001928431,0.00005080381,0.0002568864,0.00003914817,0.0003154509,0.00001759102,0.00001334466,0.001672287],"genre_scores_gemma":[0.9992334,0.00007679197,0.00009318415,0.0002101735,0.000008481693,0.00002844573,0.0000823488,0.000007802438,0.0002594339],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003527281,"threshold_uncertainty_score":0.3584302,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008561672528624074,"score_gpt":0.2559905156976051,"score_spread":0.247428843168981,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}