{"id":"W4406104417","doi":"10.3390/biomedicines13010108","title":"Oncolytic Viruses and Immunotherapy for the Treatment of Uveal Melanoma and Retinoblastoma: The Current Landscape and Novel Advances","year":2025,"lang":"en","type":"review","venue":"Biomedicines","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; McGill University Health Centre; Queen's University; University of British Columbia; McGill University","funders":"","keywords":"Oncolytic virus; Immunotherapy; Medicine; Retinoblastoma; Melanoma; Clinical trial; Radiation therapy; Cancer; Immune system; Cancer research; Immunology; Oncology; Internal medicine; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002257805,0.0002762773,0.0005885227,0.00008298365,0.0001291327,0.00001978836,0.0001725676,0.0001061961,0.000002505564],"category_scores_gemma":[0.00003740165,0.0001233864,0.0001138946,0.0001220945,0.0004606563,0.000002084023,0.00005510894,0.00006161031,1.53846e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001154703,"about_ca_system_score_gemma":0.0001853214,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008131529,"about_ca_topic_score_gemma":0.00005520932,"domain_scores_codex":[0.9990329,0.00006702903,0.0002815309,0.0003280265,0.0001122494,0.0001782724],"domain_scores_gemma":[0.9989917,0.0004247285,0.0001567724,0.0003308287,0.00005477458,0.00004122074],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004145691,0.00006577688,0.00004549389,0.002301478,0.0002848747,2.462685e-7,0.00004694538,4.713423e-8,0.0009897965,0.000006317613,0.0002398721,0.9956046],"study_design_scores_gemma":[0.001160553,0.004631731,0.00003884215,0.00100069,0.0003047482,0.0000131548,0.00004531978,0.000005445387,0.0005075983,0.00001029298,0.9921592,0.0001224342],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002925169,0.9951953,0.00006179604,0.0001681133,0.0001676867,0.001277132,0.0001835837,0.000004197428,0.00001704312],"genre_scores_gemma":[0.0003084409,0.9987082,0.00003021447,0.00004186556,0.0003507042,0.0003321893,0.00005289236,0.00002132871,0.0001541875],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9954821,"threshold_uncertainty_score":0.5031551,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03919191478060377,"score_gpt":0.389442335735272,"score_spread":0.3502504209546683,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}