{"id":"W4406104714","doi":"10.1111/mec.17641","title":"Runs of Homozygosity and Inferences in Wild Populations","year":2025,"lang":"en","type":"review","venue":"Molecular Ecology","topic":"Genetic Mapping and Diversity in Plants and Animals","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"Trent University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Runs of Homozygosity; Inbreeding; Identity by descent; Inbreeding depression; Genetics; Evolutionary biology; Disease gene identification; Population; Demography; Allele; Haplotype; Genotype; Phenotype; Gene; Single-nucleotide polymorphism","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002914984,0.0008339623,0.001882606,0.00313614,0.0003368548,0.001692408,0.001914101,0.001769006,0.003027091],"category_scores_gemma":[0.00573994,0.0004860856,0.0006151572,0.002270355,0.002100939,0.002808104,0.000983902,0.002692179,0.001984622],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009986721,"about_ca_system_score_gemma":0.00142834,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002416368,"about_ca_topic_score_gemma":0.002632672,"domain_scores_codex":[0.9992564,0.0001897572,0.0001023933,0.0002067116,0.0002145892,0.00003008483],"domain_scores_gemma":[0.9967381,0.002455425,0.000213046,0.00009242244,0.0004217288,0.00007933118],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005165166,0.00002392597,0.000430116,0.01313436,0.0001148135,0.0001901544,0.0001181191,0.000479376,0.0006089583,0.01053619,0.02035439,0.953958],"study_design_scores_gemma":[0.000009706944,0.00004938209,0.0020325,0.009047929,0.000161763,0.001281779,0.000124449,0.0001440062,0.0005048012,0.01225957,0.974329,0.00005521177],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00007966547,0.9979206,0.0004348944,0.000427096,0.0002123869,0.00000398423,0.0000291114,0.000008728234,0.0008836078],"genre_scores_gemma":[0.0006777322,0.9977575,0.0004760581,0.0003703743,0.0002995766,0.000007734016,0.00004068637,0.000004074646,0.0003663723],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00313614,"threshold_uncertainty_score":0.01541609,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02943054461721524,"score_gpt":0.3089520278091218,"score_spread":0.2795214831919066,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}