{"id":"W4406109172","doi":"10.1101/2025.01.06.631446","title":"A glycerol oxidase from Norway spruce ( <i>Picea abies</i> L. Karst.) expands biochemical and structural attributes of the GMC oxidoreductase superfamily","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Enzyme-mediated dye degradation","field":"Agricultural and Biological Sciences","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Novo Nordisk Fonden; Novo Nordisk; Diamond Light Source","keywords":"Picea abies; Karst; Oxidoreductase; SUPERFAMILY; Biochemistry; Botany; Biology; Chemistry; Enzyme; Gene; Paleontology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003006842,0.0006245796,0.0006715608,0.00005313944,0.0002640243,0.0001861677,0.00102644,0.0007491717,0.00007571332],"category_scores_gemma":[0.0004513897,0.0002892989,0.0002329421,0.00067297,0.0003747796,0.0001736188,0.0008399037,0.0008113022,0.000008700453],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001250973,"about_ca_system_score_gemma":0.0001659571,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008757267,"about_ca_topic_score_gemma":0.00006462986,"domain_scores_codex":[0.9969112,0.0002234912,0.0006936623,0.001114138,0.0005345808,0.0005228934],"domain_scores_gemma":[0.9978805,0.0003939128,0.0004707005,0.0005689564,0.0004374738,0.0002484987],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000590671,0.0000603521,0.02841939,0.00008720458,0.00008200624,0.000004789073,0.00001403808,0.000006550122,0.9703026,0.00006133771,0.0008918584,0.00001076857],"study_design_scores_gemma":[0.0003199566,0.0000405475,0.3612058,0.000265148,0.0001246463,2.190869e-8,0.0000126289,0.000114535,0.6369932,0.00001253465,0.0004846164,0.0004262676],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9894917,0.002255635,0.000005468725,0.0009282458,0.0008803032,0.000683583,0.005605621,0.000145665,0.000003754676],"genre_scores_gemma":[0.9981082,0.0002448535,0.0006256648,0.0003627101,0.0005410733,0.00008068007,0.00001923589,0.000008468181,0.000009092775],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3333094,"threshold_uncertainty_score":0.9999559,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01043139033011901,"score_gpt":0.1944501153009007,"score_spread":0.1840187249707817,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}