{"id":"W4406116391","doi":"10.1111/acel.14425","title":"Immunotherapeutic targeting of aging‐associated isoDGR motif in chronic lung inflammation","year":2025,"lang":"en","type":"article","venue":"Aging Cell","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Brock University","funders":"Institute of Aging; National Medical Research Council; Medical Research Council; Canadian Institutes of Health Research; Canada Research Chairs; Brock University; Natural Sciences and Engineering Research Council of Canada","keywords":"Inflammation; Biology; Lung; Immune system; Immunology; In vivo; Senescence; Pathology; Medicine; Cell biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003187462,0.0001169154,0.0001876596,0.0002579662,0.00009087726,0.00001182002,0.0001158005,0.0001413998,0.0004909222],"category_scores_gemma":[0.00004226719,0.0001227297,0.00006947034,0.0002650651,0.00004257058,0.0001250061,0.00004068782,0.0003041835,0.000114345],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003029612,"about_ca_system_score_gemma":0.00007936901,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003891713,"about_ca_topic_score_gemma":0.00002895094,"domain_scores_codex":[0.9990141,0.0001676673,0.000395424,0.0001689617,0.00002349013,0.0002303481],"domain_scores_gemma":[0.9994745,0.0001083176,0.0001913645,0.0001557433,0.00006599944,0.00000408824],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002228791,0.00004888002,0.005137742,0.00007903401,0.00007393873,5.848859e-7,0.0006158088,0.0002382898,0.9889857,0.0001046603,0.001770878,0.002922151],"study_design_scores_gemma":[0.001744406,0.00004143668,0.009960398,0.0003127167,0.0000420445,0.000001385333,0.000390327,0.001515685,0.954417,0.00005856116,0.03136229,0.0001537875],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9709816,0.01435774,0.0009531829,0.0003415682,0.002904383,0.000242375,0.00000103383,0.0001024103,0.01011572],"genre_scores_gemma":[0.9825512,0.0001758503,0.00001002061,0.00009549318,0.00001450309,0.000007917255,0.00008678683,0.00001072144,0.01704756],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03456878,"threshold_uncertainty_score":0.5375254,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005019012787314755,"score_gpt":0.2336978573502391,"score_spread":0.2286788445629243,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}