{"id":"W4406116391","doi":"10.1111/acel.14425","title":"Immunotherapeutic targeting of aging‐associated isoDGR motif in chronic lung inflammation","year":2025,"lang":"en","type":"article","venue":"Aging Cell","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Brock University","funders":"Institute of Aging; National Medical Research Council; Medical Research Council; Canadian Institutes of Health Research; Canada Research Chairs; Brock University; Natural Sciences and Engineering Research Council of Canada","keywords":"Inflammation; Biology; Lung; Immune system; Immunology; In vivo; Senescence; Pathology; Medicine; Cell biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002435027,0.0002888236,0.0002794391,0.0002043638,0.00007752384,0.0001369504,0.0001703171,0.0003378862,0.0004964169],"category_scores_gemma":[0.00005940225,0.00007754187,0.00015404,0.00006834442,0.0001596843,0.0001542808,0.0001539405,0.0005053831,0.0001223721],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001370948,"about_ca_system_score_gemma":0.000107533,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001275818,"about_ca_topic_score_gemma":0.0002691767,"domain_scores_codex":[0.9999099,0.00002341301,0.000006303143,0.0000150207,0.00001607921,0.0000292312],"domain_scores_gemma":[0.9999614,0.000007014525,0.0000118023,0.00000541701,0.000004915128,0.000009462932],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001366964,0.0001421325,0.0001131538,0.00006022467,0.000005263838,0.00005660833,0.00001222587,0.0001222437,0.9946791,0.0001322107,0.00004342729,0.004496785],"study_design_scores_gemma":[0.0001787236,0.006873142,0.005629863,0.00002734818,0.00005890459,0.0008836608,0.00002880113,0.002552578,0.9762057,0.0001457441,0.007406842,0.000008676669],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9854957,0.0073389,0.005660712,0.0001340737,0.00006905056,0.000074647,0.00004533805,0.00008154118,0.001099925],"genre_scores_gemma":[0.9937631,0.002188307,0.002824416,0.00006867071,0.0000314662,0.00003922692,0.00005925208,0.000006087251,0.001019404],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004964169,"threshold_uncertainty_score":0.001660705,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005019012787314755,"score_gpt":0.2336978573502391,"score_spread":0.2286788445629243,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}