{"id":"W4406146075","doi":"10.1080/17474124.2025.2450717","title":"The role of noninvasive biomarkers for monitoring cell injury in advanced liver fibrosis","year":2025,"lang":"en","type":"review","venue":"Expert Review of Gastroenterology & Hepatology","topic":"Liver Disease Diagnosis and Treatment","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network; McGill University Health Centre","funders":"","keywords":"Medicine; Cirrhosis; Natural history; Fibrosis; Chronic liver disease; Hepatic fibrosis; Liver fibrosis; Stage (stratigraphy); Liver disease; Liver injury; Intensive care medicine; Pathology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000288445,0.0005114811,0.004060246,0.0002702555,0.00005549278,0.000003036819,0.0003792226,0.0002767977,0.00002404013],"category_scores_gemma":[0.0002058097,0.0003350688,0.001386047,0.0002298141,0.0002596379,0.00003433296,0.0001814542,0.0002267071,0.000004291262],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001950972,"about_ca_system_score_gemma":0.0004192225,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005493601,"about_ca_topic_score_gemma":0.00001561334,"domain_scores_codex":[0.9967337,0.0005149007,0.001490601,0.0005791609,0.0001537593,0.0005278761],"domain_scores_gemma":[0.9970644,0.0009373343,0.0009536566,0.0007340499,0.0002008999,0.0001096489],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007300864,0.0006629681,0.02422481,0.1466225,0.001174931,0.00004262751,0.00004047818,1.545386e-8,0.00001051863,0.00002268407,0.001412892,0.8250555],"study_design_scores_gemma":[0.001668707,0.00277426,0.0004609708,0.2256877,0.003664752,0.00006971899,0.00006051773,0.000001593113,0.0004775522,0.00001127314,0.7649312,0.0001917587],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000523249,0.9951305,0.000005130613,0.0002146253,0.0004153599,0.003424375,0.0001694358,0.00001179969,0.0001054779],"genre_scores_gemma":[0.0004608319,0.9948848,0.0009892556,0.0002750633,0.00006055883,0.003117982,0.000152789,0.00003713102,0.00002153888],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8248638,"threshold_uncertainty_score":0.9999101,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01292588570809702,"score_gpt":0.3316892253399027,"score_spread":0.3187633396318057,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}