{"id":"W4406159117","doi":"10.1007/s00424-024-03062-4","title":"Lessons from a model: early glucagon dysfunction in type 2 diabetes","year":2025,"lang":"en","type":"letter","venue":"Pflügers Archiv - European Journal of Physiology","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Glucagon; Type 2 diabetes; Diabetes mellitus; Medicine; Type 1 diabetes; Internal medicine; Endocrinology; Insulin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003143828,0.00105762,0.001938804,0.0006648691,0.001572713,0.003186531,0.001808895,0.02255956,0.005311477],"category_scores_gemma":[0.01562896,0.0003890887,0.001184742,0.000393437,0.003095459,0.00760108,0.001711477,0.03370646,0.002945612],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002144526,"about_ca_system_score_gemma":0.001523539,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001420299,"about_ca_topic_score_gemma":0.001781781,"domain_scores_codex":[0.9988004,0.0004670435,0.0001577727,0.0002075953,0.0002118503,0.0001553379],"domain_scores_gemma":[0.9920554,0.005730547,0.0003122707,0.000306384,0.0007323119,0.0008632439],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.0006435215,0.0002645208,0.001952438,0.0003713847,0.00009919078,0.02615954,0.000323203,0.0004384599,0.000645083,0.03090134,0.8864009,0.0518004],"study_design_scores_gemma":[0.001742797,0.0005483609,0.002568564,0.001686853,0.0002325587,0.04127245,0.001353955,0.0024938,0.0006399974,0.3290709,0.6181405,0.0002492747],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.001009013,0.00762919,0.0005119361,0.9711039,0.01812096,0.000005031818,0.00004489539,0.0000295112,0.001545569],"genre_scores_gemma":[0.02548284,0.01702726,0.001042182,0.6848101,0.2685752,0.00004837652,0.00005872015,0.00005305687,0.00290226],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.02255956,"threshold_uncertainty_score":0.01776868,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02121897559424317,"score_gpt":0.250781504068769,"score_spread":0.2295625284745259,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}