{"id":"W4406200953","doi":"10.1002/alz.091296","title":"Longitudinal posterior‐medial functional connectivity changes with age and Alzheimer’s pathology are differentially related to memory performance depending on APOE genotype","year":2024,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Genetics and Physical Performance","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"","keywords":"Apolipoprotein E; Neuroscience; Genotype; Association (psychology); Functional connectivity; Psychology; Biology; Pathology; Medicine; Disease; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000290377,0.0002142406,0.0001968843,0.0003610584,0.0001460713,0.0002563256,0.0001572114,0.0002493759,0.002042521],"category_scores_gemma":[0.0007414733,0.0001360886,0.0001867548,0.0002682157,0.0001725337,0.0002960429,0.0001924958,0.0002332279,0.0001700791],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001236391,"about_ca_system_score_gemma":0.000104228,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002805864,"about_ca_topic_score_gemma":0.004579469,"domain_scores_codex":[0.9999261,0.00001043006,0.000005409328,0.00003223578,0.00001052729,0.00001539734],"domain_scores_gemma":[0.9995961,0.00007446552,0.0001692865,0.00005601634,0.00004731917,0.00005688523],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003387267,0.0002284897,0.9114754,0.00004795082,0.0003131203,0.0003166241,0.000440552,0.0003179437,0.07044665,0.0001344375,0.0004624882,0.01242898],"study_design_scores_gemma":[0.000003177179,0.0000784093,0.9989939,0.000001707675,0.0000161706,0.0001225959,0.00002543342,0.0001417159,0.0005215127,0.00004205594,0.00005152619,0.000001618045],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992797,0.0000976404,0.0001770979,0.00001159925,0.000001270138,0.000002234514,0.0002493889,0.000005375417,0.0001757336],"genre_scores_gemma":[0.9991878,0.00003596297,0.0001433024,0.000005684364,0.00000349827,0.00000566814,0.0003344082,0.000002630119,0.0002810486],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002805864,"threshold_uncertainty_score":0.006832957,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02391774242698603,"score_gpt":0.2465035146532047,"score_spread":0.2225857722262187,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}