{"id":"W4406216172","doi":"10.3390/biom15010091","title":"The Passage of Chaperonins to Extracellular Locations in Legionella pneumophila Requires a Functional Dot/Icm System","year":2025,"lang":"en","type":"article","venue":"Biomolecules","topic":"Legionella and Acanthamoeba research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Periplasmic space; Chaperonin; Cytoplasm; Extracellular; Immunoelectron microscopy; Secretion; Bacterial outer membrane; Biology; Mutant; Cell biology; GroEL; Complementation; Microbiology; Escherichia coli; Biochemistry; Protein folding; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002827998,0.0001225151,0.0001195927,0.0001287635,0.0001631963,0.00003387376,0.0002922888,0.0001046668,0.000001702574],"category_scores_gemma":[0.00008114089,0.00009427972,0.00007965285,0.0003503591,0.0002039832,0.000003261953,0.0001668694,0.00007406445,0.00001327283],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003858332,"about_ca_system_score_gemma":0.0001879695,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001545569,"about_ca_topic_score_gemma":0.0003075244,"domain_scores_codex":[0.998887,0.00008514415,0.0002779341,0.000302083,0.0001843149,0.0002635206],"domain_scores_gemma":[0.999324,0.00003914933,0.00005152413,0.0004135523,0.0001108438,0.00006095899],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009470673,0.00007011697,0.001035195,0.00005122482,0.00004309692,0.000008040204,0.00003273152,0.00009785294,0.9616855,0.03283714,0.002948409,0.001095934],"study_design_scores_gemma":[0.0008897731,0.0002507503,0.009864259,0.0002245803,0.00002749981,0.00002129294,0.001179299,0.000407327,0.8469771,0.0003328061,0.1395086,0.0003167192],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9727479,0.007839664,0.006764347,0.0057573,0.0003223562,0.0005692636,0.00002719193,0.00002254283,0.005949457],"genre_scores_gemma":[0.9966303,0.0001636009,0.00009443742,0.00008903809,0.00008242024,0.00007943175,0.00003609251,0.00001184061,0.00281283],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1365602,"threshold_uncertainty_score":0.3844615,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01350585778939974,"score_gpt":0.2673681503033143,"score_spread":0.2538622925139146,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}