{"id":"W4406216172","doi":"10.3390/biom15010091","title":"The Passage of Chaperonins to Extracellular Locations in Legionella pneumophila Requires a Functional Dot/Icm System","year":2025,"lang":"en","type":"article","venue":"Biomolecules","topic":"Legionella and Acanthamoeba research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Periplasmic space; Chaperonin; Cytoplasm; Extracellular; Immunoelectron microscopy; Secretion; Bacterial outer membrane; Biology; Mutant; Cell biology; GroEL; Complementation; Microbiology; Escherichia coli; Biochemistry; Protein folding; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000120012,0.0002987256,0.0002361601,0.0001441303,0.0001679081,0.0004020203,0.0001538931,0.0002404238,0.0004929759],"category_scores_gemma":[0.0001700127,0.0001858127,0.0002223612,0.0001292175,0.0002595794,0.0002446798,0.0003757181,0.0004216219,0.0003457248],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000581347,"about_ca_system_score_gemma":0.000227362,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001031652,"about_ca_topic_score_gemma":0.00147915,"domain_scores_codex":[0.9998559,0.00001816526,0.00002172281,0.00002989529,0.00004424326,0.00003012381],"domain_scores_gemma":[0.9998387,0.00002194055,0.00005073569,0.00003208012,0.00001760493,0.00003880407],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002509604,0.000008511407,0.0002604283,0.00001465933,0.000001571546,0.00005991428,0.00001045005,0.0000204218,0.9992065,0.00006311045,0.00001869433,0.0003106222],"study_design_scores_gemma":[0.00001166966,0.00009851479,0.01345475,0.000007463181,0.000009803498,0.0004157762,0.00005353353,0.001597708,0.9830768,0.00005236284,0.001211259,0.00001027198],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971067,0.0002137022,0.001863707,0.00006165291,0.00001171677,0.00001078958,0.000191366,0.00008049703,0.0004597226],"genre_scores_gemma":[0.9956683,0.0001031845,0.002440679,0.00004603376,0.000003915187,0.0000187927,0.0005567459,0.00003137625,0.001130864],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001031652,"threshold_uncertainty_score":0.004218042,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01350585778939974,"score_gpt":0.2673681503033143,"score_spread":0.2538622925139146,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}