{"id":"W4406223297","doi":"10.1002/alz.094038","title":"The role of biofluid markers in predicting near‐term cognitive impairment","year":2024,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Neurological Institute and Hospital; McGill University; Douglas Mental Health University Institute","funders":"","keywords":"Cerebrospinal fluid; Receiver operating characteristic; Medicine; Internal medicine; Cohort; Oncology; Cognitive impairment; Biomarker; Pathology; Gastroenterology; Disease; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001486578,0.001076782,0.0004878862,0.001638994,0.000350233,0.001644048,0.0004964229,0.000995495,0.001027214],"category_scores_gemma":[0.007221566,0.0002200228,0.0004872502,0.0006943736,0.0002694622,0.0006476115,0.0004915234,0.0006393215,0.0004050134],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000308531,"about_ca_system_score_gemma":0.0001991106,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003466506,"about_ca_topic_score_gemma":0.002251107,"domain_scores_codex":[0.9994521,0.000195965,0.00005411977,0.0001407435,0.00009909707,0.00005801266],"domain_scores_gemma":[0.9961125,0.0014392,0.001339149,0.0002501052,0.0005753909,0.0002837037],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001184955,0.000146285,0.9814874,0.00003819177,0.0002178141,0.0001012174,0.00007501362,0.000700439,0.001219159,0.0000607341,0.0002538363,0.01451507],"study_design_scores_gemma":[0.00002067662,0.0007152322,0.9885321,0.00003677442,0.0001938279,0.000438595,0.0001593512,0.007231282,0.001620085,0.0005266338,0.0005007703,0.00002484466],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962468,0.001266286,0.0007432501,0.00008253009,0.00002476786,0.00001237122,0.0004277656,0.00004528711,0.001150977],"genre_scores_gemma":[0.9990014,0.0001339929,0.0004785708,0.00001974804,0.00001390066,0.000009074327,0.0001564419,0.000003034719,0.000183749],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003466506,"threshold_uncertainty_score":0.007861912,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01403268981868775,"score_gpt":0.2999865540470489,"score_spread":0.2859538642283612,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}