{"id":"W4406232152","doi":"10.1038/s41594-024-01455-8","title":"A multivalent engagement of ENL with MOZ","year":2025,"lang":"en","type":"article","venue":"Nature Structural & Molecular Biology","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval","funders":"National Cancer Institute; National Heart, Lung, and Blood Institute","keywords":"Epigenetics; Zinc finger; Biology; Bromodomain; Histone acetyltransferase; Acetylation; Genetics; Gene; Chemistry; Transcription factor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001240465,0.0001900312,0.0001996716,0.00008851698,0.00005664065,0.00000735363,0.0002120015,0.0004274269,0.00001441565],"category_scores_gemma":[0.0001031918,0.0001429951,0.00009431769,0.000156161,0.0001285597,0.00000158008,0.0001316302,0.0002646447,5.961808e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001541582,"about_ca_system_score_gemma":0.00008295158,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000155295,"about_ca_topic_score_gemma":0.00001560353,"domain_scores_codex":[0.9989344,0.0001423511,0.0002169268,0.0003928222,0.00009380116,0.000219702],"domain_scores_gemma":[0.9992998,0.00001313838,0.0001080923,0.0003687361,0.00016873,0.00004147807],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001214909,0.00001267848,0.004724612,0.00002459528,0.0001395538,0.000002599111,0.00001738371,0.000151229,0.9835904,0.005840057,0.00004501216,0.005330359],"study_design_scores_gemma":[0.0006860422,0.0003712946,0.01074486,0.0000165057,0.00003871088,0.000002256714,0.00001966562,0.0000408306,0.9759576,0.002667394,0.009294634,0.0001601779],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.981804,0.006638024,0.0091887,0.0002958042,0.0002439229,0.0002774042,0.00002558736,0.00001026361,0.001516349],"genre_scores_gemma":[0.9951418,0.00009058291,0.003994805,0.0003054332,0.00004851539,0.00001446123,0.0001996701,0.00001333947,0.0001913925],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01333786,"threshold_uncertainty_score":0.5831171,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003396977899527216,"score_gpt":0.316012267542449,"score_spread":0.3126152896429218,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}