{"id":"W4406248856","doi":"10.1002/smll.202407742","title":"Photochemical Stabilization of Self‐Assembled Spherical Nucleic Acids","year":2025,"lang":"en","type":"article","venue":"Small","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Fonds de recherche du Québec – Nature et technologies; Natural Sciences and Engineering Research Council of Canada; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Canada Foundation for Innovation","keywords":"Nucleic acid; Oligonucleotide; Nuclease; Gene silencing; DNA; Biophysics; Covalent bond; Chemistry; Biochemistry; Combinatorial chemistry; Biology; Gene; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007877067,0.00009464464,0.0001372678,0.00002813786,0.00002563882,0.000006478429,0.0001098244,0.0001421416,0.000002866221],"category_scores_gemma":[0.0000682311,0.00008406751,0.00008811308,0.0001793997,0.00003244897,0.000001178955,0.00007434273,0.00005071579,7.684304e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001386836,"about_ca_system_score_gemma":0.00004604944,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004745382,"about_ca_topic_score_gemma":0.00001070613,"domain_scores_codex":[0.999385,0.00002975341,0.0001806353,0.0002262586,0.0000591215,0.0001192448],"domain_scores_gemma":[0.9995466,0.00000831109,0.00005654753,0.0002566836,0.0001045342,0.0000272571],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004201455,0.00008476313,0.003274141,0.00002036611,0.00004185821,4.10301e-7,0.000005817394,0.00000272762,0.9953244,0.0001135878,0.000326217,0.0007636377],"study_design_scores_gemma":[0.0001770931,0.00008259744,0.0005167322,0.00001554823,0.00003459586,0.000001140161,0.0000219726,0.0001283594,0.9911196,0.0001918669,0.007622559,0.00008795298],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9823444,0.00009553193,0.01490829,0.00007510251,0.00003080771,0.0001129548,0.000002640663,0.00005012776,0.002380186],"genre_scores_gemma":[0.972535,0.00006501992,0.02695809,0.000139186,0.00003376391,0.000005814858,0.00003179407,0.000007882539,0.0002234439],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0120498,"threshold_uncertainty_score":0.3428173,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007359019606274713,"score_gpt":0.261770719945112,"score_spread":0.2544117003388373,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}