{"id":"W4406248856","doi":"10.1002/smll.202407742","title":"Photochemical Stabilization of Self‐Assembled Spherical Nucleic Acids","year":2025,"lang":"en","type":"article","venue":"Small","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Fonds de recherche du Québec – Nature et technologies; Natural Sciences and Engineering Research Council of Canada; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Canada Foundation for Innovation","keywords":"Nucleic acid; Oligonucleotide; Nuclease; Gene silencing; DNA; Biophysics; Covalent bond; Chemistry; Biochemistry; Combinatorial chemistry; Biology; Gene; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001328126,0.0001924707,0.0000909439,0.0001066999,0.0001009919,0.0001561784,0.0001648531,0.0002368086,0.0006443331],"category_scores_gemma":[0.0001830776,0.00008638424,0.0001381362,0.0000638667,0.0001548423,0.0001507304,0.0001638237,0.0001922565,0.0002159163],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002637377,"about_ca_system_score_gemma":0.0001658154,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003829222,"about_ca_topic_score_gemma":0.0005808898,"domain_scores_codex":[0.9999034,0.00001341043,0.000005240832,0.00003074858,0.00003060178,0.00001652835],"domain_scores_gemma":[0.9999058,0.0000204888,0.00003324715,0.00001010486,0.00002142899,0.000008912699],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001290492,0.000005220978,0.00002863228,0.0000193201,0.000002627682,0.00001188647,0.00001250081,0.0001699414,0.9978725,0.0001723592,0.00002774233,0.00166451],"study_design_scores_gemma":[0.000002505192,0.00005466421,0.0002294367,0.000001116685,0.000002176563,0.00001988539,0.000004493921,0.001189971,0.9974715,0.00002868879,0.0009940792,0.000001676222],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9707713,0.002120827,0.0230355,0.00009931024,0.00006824029,0.0000372112,0.00006653262,0.0002026437,0.003598464],"genre_scores_gemma":[0.9920052,0.000482847,0.004757282,0.00004746691,0.000009114082,0.00001753968,0.00006243206,0.00002169913,0.002596397],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006443331,"threshold_uncertainty_score":0.002155483,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007359019606274713,"score_gpt":0.261770719945112,"score_spread":0.2544117003388373,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}