{"id":"W4406291439","doi":"10.1093/bbb/zbaf001","title":"<i>Tetragonia tetragonioides</i> extract prevented high-fat-diet-induced obesity and changed hepatic and adipose transcriptomic signatures in C57BL/6J male mice","year":2025,"lang":"en","type":"article","venue":"Bioscience Biotechnology and Biochemistry","topic":"Adipokines, Inflammation, and Metabolic Diseases","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Ministry of Science and ICT, South Korea; National Research Foundation of Korea; Ministry of Food and Drug Safety; Ministry of Education","keywords":"Adipose tissue; Obesity; Transcriptome; Endocrinology; Lipid metabolism; Internal medicine; White adipose tissue; Biology; Immune system; Phenotype; Gene expression; Gene; Medicine; Immunology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002246497,0.000257217,0.0003705687,0.0002636859,0.0001751577,0.00002986077,0.0001614286,0.0006189026,0.00001834264],"category_scores_gemma":[0.0002875778,0.000225994,0.00003981175,0.0005537137,0.0007691339,0.0001053868,0.00007083898,0.0003532845,8.467637e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000392704,"about_ca_system_score_gemma":0.0001528511,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001183825,"about_ca_topic_score_gemma":0.0000621957,"domain_scores_codex":[0.9985355,0.00002914929,0.0003143611,0.0006337306,0.0001321182,0.0003552],"domain_scores_gemma":[0.9993947,0.00005470406,0.00009369261,0.0002725193,0.00004068012,0.0001437589],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001812836,0.0001923551,0.01490792,0.0004035457,0.0000264832,0.00003053507,0.00005818123,8.953658e-8,0.9789788,0.0002063904,0.00009760234,0.004916781],"study_design_scores_gemma":[0.001352069,0.0001460628,0.1543115,0.0002975694,0.0001415482,0.00006380791,0.0001773881,0.0001247745,0.8422862,0.0001829939,0.0006919138,0.0002242022],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9854448,0.01100869,0.00004472034,0.002713626,0.0001399428,0.0004050891,0.00003640363,0.0001057768,0.0001009455],"genre_scores_gemma":[0.9965451,0.001897029,0.0004622492,0.0003947534,0.00004371903,0.00002604201,0.00001598988,0.000008149726,0.0006069786],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1394036,"threshold_uncertainty_score":0.9215767,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006516114068580807,"score_gpt":0.2359980649037345,"score_spread":0.2294819508351537,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}