{"id":"W4406312686","doi":"10.1212/nxg.0000000000200232","title":"Neonatal Encephalopathy","year":2025,"lang":"en","type":"article","venue":"Neurology Genetics","topic":"Genomics and Rare Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Women and Children’s Health Research Institute; University of Toronto; SickKids Foundation; Hospital for Sick Children; Alberta Health Services; McMaster Children's Hospital; University of Alberta","funders":"National Heart, Lung, and Blood Institute; Uniwersytet Warszawski; International Society on Thrombosis and Haemostasis","keywords":"In silico; Gene; Encephalopathy; Pathogenicity; Biology; Copy-number variation; Genetic variants; Genetics; Medicine; Computational biology; Bioinformatics; Genome; Internal medicine; Genotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002717597,0.0006697256,0.0005097518,0.0006798501,0.0006296071,0.0006046111,0.0004893475,0.0006655694,0.01946851],"category_scores_gemma":[0.001642562,0.0001023091,0.0003173181,0.0006797334,0.0003580881,0.0005067898,0.0008774519,0.0008457304,0.00532857],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007467204,"about_ca_system_score_gemma":0.0008750407,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002320868,"about_ca_topic_score_gemma":0.001578261,"domain_scores_codex":[0.9996915,0.00005866847,0.0000429416,0.00006133335,0.00006322339,0.00008231898],"domain_scores_gemma":[0.9996388,0.00007320636,0.00007480909,0.00003631731,0.00009203167,0.00008480166],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00115061,0.0002872399,0.1237018,0.002426537,0.000216933,0.272401,0.001027784,0.0008816486,0.01296866,0.03116068,0.07109297,0.4826841],"study_design_scores_gemma":[0.00009160527,0.0003027958,0.06503197,0.001897382,0.0001573152,0.5417494,0.0009509371,0.000806415,0.009509593,0.01790121,0.3615357,0.00006567312],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"other","genre_gemma":"empirical","genre_scores_codex":[0.3570807,0.09232615,0.02989267,0.0193871,0.004692156,0.000784329,0.01101331,0.002162545,0.482661],"genre_scores_gemma":[0.8693974,0.03103126,0.0111305,0.008765946,0.001067112,0.0004860048,0.007341342,0.000242521,0.070538],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.01946851,"threshold_uncertainty_score":0.06512868,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003484937414979425,"score_gpt":0.2267427667924162,"score_spread":0.2232578293774367,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}