{"id":"W4406324155","doi":"10.3390/idr17010007","title":"Safety and Efficacy of a 48-Month Efinaconazole 10% Solution Treatment/Maintenance Regimen: 24-Month Daily Use Followed by 24-Month Intermittent Use","year":2025,"lang":"en","type":"article","venue":"Infectious Disease Reports","topic":"Nail Diseases and Treatments","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Mediprobe Research (Canada); University of Toronto","funders":"Health Canada; Bausch Health","keywords":"Medicine; Cure rate; Clinical trial; Regimen; Adverse effect; Clinical efficacy; Surgery; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001479627,0.0002918855,0.0006651306,0.0002057942,0.0002492213,0.0002855503,0.0002812537,0.0005805715,0.001300185],"category_scores_gemma":[0.001870851,0.000117151,0.0004906806,0.0001841252,0.0002655314,0.0003204645,0.0001352686,0.0007625267,0.000270249],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003100076,"about_ca_system_score_gemma":0.0004152689,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004265987,"about_ca_topic_score_gemma":0.0005181279,"domain_scores_codex":[0.9994407,0.0002481696,0.00005074839,0.00008695704,0.0001217179,0.00005156246],"domain_scores_gemma":[0.9983912,0.0003516992,0.0007053131,0.0001540313,0.0001633676,0.0002342743],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.3535342,0.02885416,0.133025,0.0006583434,0.0009273215,0.0003327187,0.0003246033,0.001633758,0.05544148,0.00009571447,0.001418436,0.4237542],"study_design_scores_gemma":[0.02248864,0.5805472,0.3807383,0.00009446657,0.0006321841,0.0008304651,0.00007597735,0.002128009,0.01052172,0.00007477996,0.001839697,0.00002863897],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982937,0.0007890865,0.0001685923,0.00004994241,0.00001229487,0.000101115,0.0001211902,0.00001378234,0.0004503439],"genre_scores_gemma":[0.9991001,0.0001692019,0.0002347062,0.00004113458,0.00003385723,0.00008368348,0.0001354361,0.000002311651,0.0001996437],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001479627,"threshold_uncertainty_score":0.007825077,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01123459291580956,"score_gpt":0.2629736877555263,"score_spread":0.2517390948397167,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}