{"id":"W4406328422","doi":"10.3390/vaccines13010066","title":"Live Plague Vaccine Development: Past, Present, and Future","year":2025,"lang":"en","type":"review","venue":"Vaccines","topic":"Yersinia bacterium, plague, ectoparasites research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Russian Science Foundation; Government of Canada; Canadian Food Inspection Agency","keywords":"Plague (disease); Reactogenicity; Immunogenicity; Vaccination; Biology; Virology; Immune system; Attenuated vaccine; Immunology; Medicine; Virulence; Gene; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00136738,0.0007120625,0.001091676,0.00178773,0.0003009384,0.001301748,0.001007443,0.001587855,0.002682927],"category_scores_gemma":[0.001383046,0.0003273436,0.0004536534,0.001922054,0.0007545179,0.002566155,0.0008033992,0.002023787,0.001333419],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007953395,"about_ca_system_score_gemma":0.001642626,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008753442,"about_ca_topic_score_gemma":0.001452722,"domain_scores_codex":[0.9997478,0.00005549954,0.00003324494,0.00004736817,0.0000775029,0.0000386276],"domain_scores_gemma":[0.999278,0.0003690603,0.00007138208,0.00002112241,0.0001715368,0.00008892746],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001144073,0.00007809209,0.0001988993,0.01669965,0.00006409483,0.000177737,0.00009938617,0.0004860151,0.001963254,0.008005378,0.03545274,0.9366603],"study_design_scores_gemma":[0.00001495917,0.0001198708,0.0004294925,0.003432251,0.00006217594,0.0005482567,0.00007153575,0.00009107322,0.0003757559,0.003438115,0.9914004,0.00001613106],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00009798616,0.9982049,0.0001203329,0.0007468502,0.0003087227,0.000002313129,0.000009643441,0.00000522187,0.0005040109],"genre_scores_gemma":[0.0005076142,0.998548,0.0001674018,0.0003195231,0.0002109266,0.00000430133,0.00001484122,0.000001285048,0.0002260781],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002682927,"threshold_uncertainty_score":0.008975267,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01685103471118267,"score_gpt":0.3187862347887352,"score_spread":0.3019352000775526,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}