{"id":"W4406354645","doi":"10.1186/s40168-024-02004-7","title":"Characterization of liver, adipose, and fecal microbiome in obese patients with MASLD: links with disease severity and metabolic dysfunction parameters","year":2025,"lang":"en","type":"article","venue":"Microbiome","topic":"Liver Disease Diagnosis and Treatment","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Western Hospital; Sunnybrook Health Science Centre; University Health Network; University of Toronto; Toronto General Hospital; Health Sciences Centre","funders":"Canadian Institutes of Health Research; Canadian Liver Foundation; American College of Gastroenterology","keywords":"Biology; Adipose tissue; Microbiome; Fatty liver; Steatohepatitis; Fibrosis; Disease; Cirrhosis; Steatosis; Immune system; Liver disease; Immunology; Internal medicine; Bioinformatics; Endocrinology; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004426228,0.0001840873,0.0003135734,0.0002902482,0.00004004427,0.00002326441,0.00003017554,0.0000778161,0.00001354742],"category_scores_gemma":[0.00000696143,0.0001330728,0.00003118265,0.0003608297,0.0001334305,0.0001321907,0.00003959313,0.00009082091,0.00000169747],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005478609,"about_ca_system_score_gemma":0.00007145394,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000139232,"about_ca_topic_score_gemma":0.00003357369,"domain_scores_codex":[0.9992012,0.00003971507,0.0001856196,0.0003275384,0.00008205916,0.000163892],"domain_scores_gemma":[0.9995038,0.00002183751,0.00007866567,0.0001752723,0.00008848937,0.0001319361],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001845241,0.001804615,0.9355093,0.0005396291,0.000306024,0.00003721431,0.0001768155,5.640743e-7,0.05530182,0.00001263796,0.00002596356,0.004440189],"study_design_scores_gemma":[0.005358884,0.0003121837,0.9804055,0.0005811535,0.0006886315,0.000004560343,0.00001091756,0.00001960285,0.01222557,0.000003987147,0.0002616813,0.0001273325],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997517,0.001162784,0.00002247837,0.0001792523,0.00003658757,0.0007822698,0.0002712377,0.00001748966,0.00001082811],"genre_scores_gemma":[0.9982617,0.0003728419,0.0002735074,0.0002591166,0.000006392209,0.00004262148,0.0006823182,0.00001374339,0.00008769594],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04489622,"threshold_uncertainty_score":0.5426551,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004085383622432166,"score_gpt":0.1937649388715002,"score_spread":0.1896795552490681,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}