{"id":"W4406362281","doi":"10.1038/s41467-025-55903-0","title":"GGCX promotes Eurasian avian-like H1N1 swine influenza virus adaption to interspecies receptor binding","year":2025,"lang":"en","type":"article","venue":"Nature Communications","topic":"Influenza Virus Research Studies","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ministry of Agriculture","funders":"National Key Research and Development Program of China; Biotechnology and Biological Sciences Research Council; Fundamental Research Funds for the Central Universities; Huazhong Agricultural University; Natural Science Foundation of Hubei Province; Natural Science Foundation of Hebei Province; National Natural Science Foundation of China","keywords":"Biology; Virology; Virus; Viral replication; Influenza A virus; Receptor; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001704325,0.0002499574,0.0001935787,0.0001034813,0.0001089246,0.0002608044,0.0001693537,0.0002891504,0.001732809],"category_scores_gemma":[0.0001344264,0.00009411834,0.0002056245,0.00006591573,0.000212825,0.0000961048,0.0002662889,0.0003146689,0.0003210295],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001678241,"about_ca_system_score_gemma":0.0002165661,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005137312,"about_ca_topic_score_gemma":0.00074053,"domain_scores_codex":[0.9998889,0.00002088237,0.00001037362,0.0000261249,0.00002708358,0.00002660826],"domain_scores_gemma":[0.9999185,0.00001377708,0.00002758248,0.000008900443,0.000008181897,0.00002313437],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000109736,0.00002021811,0.0003802702,0.00004709332,0.000006581297,0.0001073916,0.0000147619,0.0001153357,0.9974813,0.000148105,0.00008020415,0.001488966],"study_design_scores_gemma":[0.00004389653,0.0005101475,0.009337973,0.00001560167,0.0000363224,0.0005953736,0.00006962335,0.002152542,0.9786048,0.0001245642,0.008497417,0.00001187266],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9913918,0.001292205,0.004013153,0.0001658945,0.00007429926,0.00004230094,0.0003078732,0.0001424566,0.002570031],"genre_scores_gemma":[0.9945803,0.0005346398,0.002308371,0.00008665457,0.000006919408,0.0000198811,0.0002512196,0.00002777264,0.002184246],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001732809,"threshold_uncertainty_score":0.00579679,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08767087821079396,"score_gpt":0.4283676845141333,"score_spread":0.3406968063033394,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}