{"id":"W4406364656","doi":"10.1182/blood.2023022416","title":"How I diagnose and treat systemic mastocytosis with an associated hematologic neoplasm","year":2025,"lang":"en","type":"article","venue":"Blood","topic":"Mast cells and histamine","field":"Immunology and Microbiology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Thomas Hospital","funders":"","keywords":"Systemic mastocytosis; Medicine; Myeloproliferative neoplasm; Hematologic Neoplasms; Internal medicine; Quality of life (healthcare); Systemic therapy; Clinical trial; Oncology; Intensive care medicine; Bone marrow; Cancer; Myelofibrosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00100037,0.0006215139,0.0007869839,0.001309216,0.001040933,0.002626364,0.0007642038,0.003799448,0.004225917],"category_scores_gemma":[0.004060317,0.000330193,0.0006625215,0.0003763027,0.001421746,0.003284681,0.001150076,0.005404306,0.004693331],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007007095,"about_ca_system_score_gemma":0.00108844,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001334269,"about_ca_topic_score_gemma":0.00184354,"domain_scores_codex":[0.9993588,0.0001977666,0.00009832253,0.00006375925,0.0001914553,0.00008995313],"domain_scores_gemma":[0.9991902,0.00020336,0.0001179628,0.00003917163,0.0001945294,0.0002548697],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"case_report","study_design_scores_codex":[0.0002921117,0.0005238008,0.04532297,0.001279155,0.0001419685,0.0780625,0.001686548,0.001138237,0.007814602,0.004711743,0.3455128,0.5135135],"study_design_scores_gemma":[0.0001689355,0.00115615,0.03911517,0.00633298,0.000227162,0.4290493,0.01085957,0.002259744,0.004957032,0.03066998,0.4749213,0.0002828099],"study_design_candidate":"case_report","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.05569976,0.1210804,0.05559013,0.6173095,0.03262184,0.0009098704,0.000428543,0.001538428,0.1148215],"genre_scores_gemma":[0.4039964,0.1473317,0.08597864,0.2531002,0.07416678,0.0007045081,0.0006152458,0.0004487595,0.03365782],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.004225917,"threshold_uncertainty_score":0.01413709,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00576380637186202,"score_gpt":0.1898144024530972,"score_spread":0.1840505960812352,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}