{"id":"W4406382201","doi":"10.5489/cuaj.8901","title":"Neoadjuvant systemic therapy in managing locally advanced renal cancer before surgery","year":2025,"lang":"en","type":"review","venue":"Canadian Urological Association Journal","topic":"Renal cell carcinoma treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Systemic therapy; Neoadjuvant therapy; Oncology; Internal medicine; Nephrectomy; Confidence interval; Meta-analysis; Randomized controlled trial; Population; Cohort; Cancer; Surgery; Breast cancer; Kidney","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00419208,0.0005819194,0.003091333,0.00224115,0.0002916919,0.001069804,0.0007146444,0.00093529,0.002397014],"category_scores_gemma":[0.007964075,0.0003247599,0.002438856,0.002377828,0.0005717065,0.0006370996,0.0003695608,0.0008826724,0.0001390092],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002728298,"about_ca_system_score_gemma":0.006546378,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01443092,"about_ca_topic_score_gemma":0.0318281,"domain_scores_codex":[0.9976749,0.001295382,0.0003870353,0.0001756449,0.0003988606,0.00006818282],"domain_scores_gemma":[0.9941444,0.004416409,0.000871363,0.00007095253,0.000417523,0.00007931256],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001272339,0.00007863913,0.001677216,0.5130047,0.007032551,0.0001409363,0.0001377878,0.0005906373,0.0009710868,0.00121107,0.005433046,0.46845],"study_design_scores_gemma":[0.00255487,0.002175671,0.01874805,0.6356044,0.06880498,0.002394418,0.0004415281,0.0008025919,0.002478368,0.001722795,0.2641474,0.0001249917],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002313258,0.9994924,0.0000274113,0.00007984546,0.00003418644,0.00001106391,0.000009101655,8.058711e-7,0.0001138021],"genre_scores_gemma":[0.008427137,0.9909492,0.000211736,0.000174594,0.00009661473,0.00003892881,0.00002623468,0.000001055299,0.00007441284],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01443092,"threshold_uncertainty_score":0.02869385,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02799669195020883,"score_gpt":0.28561989735681,"score_spread":0.2576232054066012,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}