{"id":"W4406385486","doi":"10.1001/jamasurg.2024.6048","title":"Safety and Efficacy of Tranexamic Acid in General Surgery","year":2025,"lang":"en","type":"letter","venue":"JAMA Surgery","topic":"Blood transfusion and management","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Impact; McMaster University; Population Health Research Institute","funders":"","keywords":"Medicine; Tranexamic acid; Perioperative; Randomized controlled trial; Placebo; Surgery; Clinical trial; Anesthesia; Internal medicine; Blood loss","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007774154,0.0003233995,0.001520956,0.001110994,0.00002594563,0.00001758738,0.00007457474,0.0006871574,0.0002565342],"category_scores_gemma":[0.000225618,0.0002971109,0.0004463159,0.0004333144,0.00009169959,0.00005088357,0.00004525487,0.001136095,0.000006469373],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005088141,"about_ca_system_score_gemma":0.0002867741,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002266268,"about_ca_topic_score_gemma":0.00001849925,"domain_scores_codex":[0.9976493,0.0001740726,0.0009077013,0.0004792658,0.0003918605,0.0003978288],"domain_scores_gemma":[0.9976625,0.001597969,0.0001555608,0.0004602492,0.00005315962,0.00007058422],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004127797,0.0001424981,0.007026756,0.002542876,0.0002240027,0.00156341,0.00005238656,6.967611e-7,0.0001370272,0.00001516994,0.9315522,0.05633023],"study_design_scores_gemma":[0.001535288,0.00001696426,0.1130402,0.001766612,0.0002918241,0.00003735697,0.000009647599,0.00001101898,0.0004177395,0.00001080226,0.882596,0.0002665843],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.1061439,0.002591152,0.00008222058,0.8818357,0.001628493,0.001059796,0.00008735455,0.0001018109,0.006469585],"genre_scores_gemma":[0.05112102,0.01274933,0.0001407234,0.9180636,0.002155435,0.00005538133,0.001403954,0.0001020181,0.0142085],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.1060134,"threshold_uncertainty_score":0.9999481,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.018857026745445,"score_gpt":0.2431854139900169,"score_spread":0.2243283872445719,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}