{"id":"W4406385486","doi":"10.1001/jamasurg.2024.6048","title":"Safety and Efficacy of Tranexamic Acid in General Surgery","year":2025,"lang":"en","type":"letter","venue":"JAMA Surgery","topic":"Blood transfusion and management","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Impact; McMaster University; Population Health Research Institute","funders":"","keywords":"Medicine; Tranexamic acid; Perioperative; Randomized controlled trial; Placebo; Surgery; Clinical trial; Anesthesia; Internal medicine; Blood loss","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004318034,0.0002975168,0.001017789,0.0003374266,0.0002048861,0.0006924694,0.0003271034,0.0007046457,0.001616798],"category_scores_gemma":[0.01538147,0.0001466361,0.0012426,0.0005270449,0.0004616369,0.0004266973,0.0003902142,0.00077604,0.0001594351],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003897601,"about_ca_system_score_gemma":0.0006835034,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003379981,"about_ca_topic_score_gemma":0.0005787506,"domain_scores_codex":[0.9970176,0.001842947,0.000361909,0.000217806,0.0004360176,0.0001236764],"domain_scores_gemma":[0.9916651,0.003020326,0.004326993,0.000338408,0.0002765849,0.0003725387],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.286909,0.0009519269,0.1890235,0.01127017,0.008842335,0.0004801885,0.0003247932,0.00134597,0.00543337,0.0009238001,0.004358223,0.4901367],"study_design_scores_gemma":[0.09527443,0.1829689,0.6712332,0.004553283,0.0139308,0.002859501,0.0004114009,0.004004767,0.006136784,0.003291524,0.01520116,0.0001342883],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"commentary","genre_scores_codex":[0.8934942,0.09875199,0.00082916,0.001767913,0.0002457305,0.0002543091,0.001055222,0.00003150738,0.003569856],"genre_scores_gemma":[0.9900348,0.008293878,0.0003965686,0.0004617764,0.0001572186,0.0001151903,0.0003164472,0.000004633024,0.0002195872],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.004318034,"threshold_uncertainty_score":0.02283621,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.018857026745445,"score_gpt":0.2431854139900169,"score_spread":0.2243283872445719,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}