{"id":"W4406385834","doi":"10.1038/s41375-024-02506-1","title":"Daratumumab plus lenalidomide/dexamethasone in untreated multiple myeloma: analysis of key subgroups of the MAIA study","year":2025,"lang":"en","type":"article","venue":"Leukemia","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia; BC Cancer Agency; Institute of Cancer Research; University of Alberta; University of Calgary","funders":"Janssen Research and Development","keywords":"Lenalidomide; Daratumumab; Dexamethasone; Multiple myeloma; Internal medicine; Oncology; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004136224,0.0002143774,0.0009546377,0.0008285241,0.00006607499,0.00001093951,0.0002799426,0.000112896,0.000099285],"category_scores_gemma":[0.000659854,0.0001409603,0.00030126,0.003904363,0.0001588274,0.00005228224,0.0001702356,0.0002934512,0.000006068367],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009368224,"about_ca_system_score_gemma":0.000574016,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.009750238,"about_ca_topic_score_gemma":0.006822551,"domain_scores_codex":[0.9978103,0.0002892367,0.0006312574,0.0003798966,0.0005363675,0.000352965],"domain_scores_gemma":[0.9981723,0.0004638455,0.0001764188,0.0009037959,0.0001892881,0.00009433753],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002120513,0.0007736215,0.9845655,0.0001018952,0.003540721,0.0001098677,0.000999302,0.0006346124,0.004885538,0.00006800556,0.0001065557,0.002093853],"study_design_scores_gemma":[0.01621164,0.0002401631,0.9573375,0.0001365301,0.001599622,0.000002274128,0.0008822295,0.01202286,0.01141446,0.00002254371,0.00004404908,0.00008611973],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960769,0.0002931768,0.00004653502,0.0001315093,0.00005626425,0.001188686,0.00005380491,0.00002155369,0.002131515],"genre_scores_gemma":[0.9980233,0.0000223521,0.0002015867,0.0000454012,0.00001102563,0.0000646563,0.00005359656,0.00001446291,0.001563639],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.027228,"threshold_uncertainty_score":0.9968439,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02056087022951229,"score_gpt":0.309989620882545,"score_spread":0.2894287506530327,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}