{"id":"W4406387412","doi":"10.5435/jaaosglobal-d-23-00276","title":"Amniotic Tissue Injections Are an Effective Alternative to Corticosteroid Injections for Pain Relief and Function in Patients With Severe Knee Osteoarthritis: A Double-Blind, Randomized, Prospective Study","year":2025,"lang":"en","type":"article","venue":"JAAOS Global Research and Reviews","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Atkinson Foundation","funders":"Integra LifeSciences","keywords":"Medicine; Osteoarthritis; Pain relief; Randomized controlled trial; Double blind; Surgery; Corticosteroid; Anesthesia; Alternative medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002895462,0.001608634,0.004257042,0.0006396552,0.000514005,0.001132201,0.00100831,0.002342935,0.004126641],"category_scores_gemma":[0.002775714,0.001027821,0.001948424,0.0007053942,0.002019833,0.001150183,0.0004773358,0.002167575,0.0007284891],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004898833,"about_ca_system_score_gemma":0.001049205,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003742451,"about_ca_topic_score_gemma":0.0005459902,"domain_scores_codex":[0.9976923,0.001266247,0.0002680141,0.0003083233,0.0002865708,0.0001786531],"domain_scores_gemma":[0.9972862,0.00102561,0.0008149449,0.0002341599,0.0001857449,0.0004534264],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9746313,0.01187981,0.0007295478,0.0005203915,0.000636886,0.00002644358,0.00004096525,0.00008124668,0.002467796,0.0000357428,0.0001149904,0.00883489],"study_design_scores_gemma":[0.7828447,0.2138526,0.001876779,0.00002905622,0.0004347698,0.00002662555,0.00002147975,0.0001781652,0.0004782387,0.00003174007,0.0002131551,0.00001265819],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9894413,0.005309726,0.0005996427,0.000232783,0.0004483481,0.003079411,0.0003153474,0.00004212944,0.0005313872],"genre_scores_gemma":[0.9870291,0.003623741,0.001725379,0.0005930702,0.001073905,0.004536946,0.0003708087,0.0000116974,0.001035459],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004257042,"threshold_uncertainty_score":0.01531285,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0299482836862363,"score_gpt":0.3647321520425729,"score_spread":0.3347838683563366,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}