{"id":"W4406387412","doi":"10.5435/jaaosglobal-d-23-00276","title":"Amniotic Tissue Injections Are an Effective Alternative to Corticosteroid Injections for Pain Relief and Function in Patients With Severe Knee Osteoarthritis: A Double-Blind, Randomized, Prospective Study","year":2025,"lang":"en","type":"article","venue":"JAAOS Global Research and Reviews","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Atkinson Foundation","funders":"Integra LifeSciences","keywords":"Medicine; Osteoarthritis; Pain relief; Randomized controlled trial; Double blind; Surgery; Corticosteroid; Anesthesia; Alternative medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002113868,0.0002811578,0.0009622718,0.0003976638,0.0003666331,0.0001163933,0.00006139134,0.0001043057,0.000007177809],"category_scores_gemma":[0.0009306103,0.0001987411,0.00006992043,0.001088811,0.0001524289,0.0002272307,0.0000932307,0.0003222345,0.000008983578],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003898375,"about_ca_system_score_gemma":0.00009780787,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002864487,"about_ca_topic_score_gemma":0.004530965,"domain_scores_codex":[0.9970266,0.001004643,0.0004571378,0.0007216573,0.0003410245,0.0004489839],"domain_scores_gemma":[0.9982992,0.0003590244,0.0001086237,0.0002965462,0.0006383798,0.0002982623],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.3395562,0.002850644,0.213288,0.0003402116,0.0002484921,0.00001920656,0.0008669532,0.000002041661,0.00002649741,0.000710992,0.0001736799,0.441917],"study_design_scores_gemma":[0.6481178,0.1404087,0.1989935,0.003509014,0.0005434264,0.00001925511,0.003209249,0.00001532164,0.00009275469,0.002665684,0.00203647,0.0003887897],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9461787,0.004766344,0.0005690479,0.0001721088,0.0001926822,0.04749433,0.00006199013,0.00003696912,0.0005277701],"genre_scores_gemma":[0.9855803,0.0004040123,0.0003941174,0.0001298795,0.00008458454,0.01262366,0.00006134505,0.00002050593,0.0007015622],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4415283,"threshold_uncertainty_score":0.8104425,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0299482836862363,"score_gpt":0.3647321520425729,"score_spread":0.3347838683563366,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}