{"id":"W4406410139","doi":"10.1016/j.mucimm.2025.01.005","title":"T follicular helper cell expansion and hyperimmunoglobulinemia with spontaneous IgE production to dietary antigens in IgA-deficient mice","year":2025,"lang":"en","type":"article","venue":"Mucosal Immunology","topic":"Immunodeficiency and Autoimmune Disorders","field":"Immunology and Microbiology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; Fonds de Recherche du Québec - Santé; National Institutes of Health; Food Allergy Science Initiative","keywords":"Immunoglobulin E; Immunology; Follicular phase; Antigen; Immunoglobulin A; Biology; Secretory IgA; Medicine; Antibody; Immunoglobulin G; Endocrinology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003256245,0.0004329884,0.000594255,0.0005307569,0.0004068893,0.00002868171,0.000382218,0.0004141911,0.00007558891],"category_scores_gemma":[0.00008910135,0.0003812725,0.00008828482,0.0007577938,0.0004328912,0.0001293676,0.0002804364,0.0006317669,0.0002194507],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001190554,"about_ca_system_score_gemma":0.0001581141,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009009013,"about_ca_topic_score_gemma":0.0001216711,"domain_scores_codex":[0.9974275,0.0002755024,0.0005564101,0.000846062,0.00006248226,0.0008320995],"domain_scores_gemma":[0.9990326,0.00008818693,0.0001138404,0.0006404986,0.0001124835,0.00001243944],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001469311,0.0005890537,0.00113825,0.0000501362,0.000123248,0.0001188297,0.001638171,0.0002622459,0.9829146,0.0002072869,0.0001519563,0.01133693],"study_design_scores_gemma":[0.007304382,0.002191065,0.1641991,0.0005544256,0.0002317803,0.002535907,0.009713936,0.00004561859,0.7261193,0.0001855632,0.08528952,0.001629414],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9255596,0.06973299,0.0001198199,0.001138473,0.001424584,0.0007419776,0.00001076744,0.0001265071,0.001145299],"genre_scores_gemma":[0.9955144,0.0007183499,0.000149235,0.000451153,0.000005029424,0.00009026601,0.0001142013,0.00003231316,0.002925035],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2567953,"threshold_uncertainty_score":0.9998639,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004756936013889542,"score_gpt":0.2080723506955713,"score_spread":0.2033154146816817,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}