{"id":"W4406430875","doi":"10.3390/cancers17020281","title":"MET Activation in Lung Cancer and Response to Targeted Therapies","year":2025,"lang":"en","type":"review","venue":"Cancers","topic":"Liver physiology and pathology","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; National Cancer Institute; BC Cancer Foundation; Terry Fox Research Institute","keywords":"Carcinogenesis; Receptor tyrosine kinase; Cancer research; Signal transduction; Biology; Tyrosine kinase; Hepatocyte Growth Factor Receptor; Cancer; Bioinformatics; Hepatocyte growth factor; Medicine; Receptor; Cell biology; Genetics; C-Met","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003084154,0.0004456364,0.0008167541,0.001629386,0.0001596739,0.0006270102,0.0004786701,0.0006622406,0.002322664],"category_scores_gemma":[0.00046653,0.0001539603,0.0003438577,0.001280802,0.0002276798,0.0005297831,0.0004408405,0.001023203,0.001221537],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005111775,"about_ca_system_score_gemma":0.0005685802,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009416936,"about_ca_topic_score_gemma":0.002027925,"domain_scores_codex":[0.9998617,0.00002832617,0.00002241874,0.00002292536,0.00005196056,0.00001268969],"domain_scores_gemma":[0.9998763,0.00005561562,0.00002173457,0.000002760159,0.00003267441,0.00001100954],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008849352,0.00005153479,0.0003329287,0.01513132,0.00009389457,0.0003451485,0.00005676433,0.0003843392,0.001552417,0.002334545,0.02508382,0.9545447],"study_design_scores_gemma":[0.00002155153,0.0001368353,0.001994369,0.005708858,0.0001559766,0.003855311,0.0000641702,0.0001520338,0.0005524212,0.001472587,0.9858645,0.0000213932],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001234558,0.9988825,0.00004722262,0.0001353856,0.0000698451,0.000002147481,0.00001085303,0.000003553012,0.0007250237],"genre_scores_gemma":[0.001068241,0.9981421,0.00007338475,0.0001341275,0.0001062682,0.000003993497,0.00002193522,8.642787e-7,0.0004489658],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002322664,"threshold_uncertainty_score":0.007770121,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03410187347433004,"score_gpt":0.384813122279608,"score_spread":0.3507112488052779,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}