{"id":"W4406450162","doi":"10.1016/j.devcel.2024.12.039","title":"mTor limits autophagy to facilitate cell volume expansion and rapid wound repair in Drosophila embryos","year":2025,"lang":"en","type":"article","venue":"Developmental Cell","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ted Rogers Centre for Heart Research; University of Toronto","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Canada Foundation for Innovation","keywords":"Biology; Autophagy; Drosophila (subgenus); PI3K/AKT/mTOR pathway; Cell biology; Embryo; Genetics; Signal transduction; Gene; Apoptosis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001816122,0.0002527293,0.0003415524,0.0002842521,0.0001008053,0.00001827814,0.00009964877,0.0001277335,0.0002669221],"category_scores_gemma":[0.00002256261,0.0002463641,0.0000824237,0.0003863106,0.00005435184,0.0000927859,0.0001000303,0.0001848359,0.0003044826],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002159695,"about_ca_system_score_gemma":0.0003517515,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004409019,"about_ca_topic_score_gemma":0.00000850561,"domain_scores_codex":[0.9984732,0.00004346876,0.0003916039,0.0005087155,0.0002173556,0.0003656137],"domain_scores_gemma":[0.9994042,0.00004054954,0.00004086224,0.0002304602,0.00004045859,0.0002434562],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.003347975,0.003025959,0.07983384,0.002300782,0.0002803169,0.001952717,0.01717782,0.0000234287,0.7375129,0.000128762,0.1059071,0.0485083],"study_design_scores_gemma":[0.005929682,0.0004330596,0.5680259,0.0003120894,0.00005805779,0.00002358363,0.001186325,0.00024029,0.2883646,0.0002619877,0.1345958,0.0005686646],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9788444,0.001844072,0.00003098669,0.0004115749,0.0002498859,0.0007440321,0.00002380095,0.000142543,0.01770869],"genre_scores_gemma":[0.9400886,0.0002113934,0.002835036,0.003389728,0.00003526482,0.0000776669,0.00004940725,0.00002443362,0.05328846],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4881921,"threshold_uncertainty_score":0.9999989,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01961499737123436,"score_gpt":0.2474184832520909,"score_spread":0.2278034858808566,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}