{"id":"W4406469350","doi":"10.1111/liv.16239","title":"Development and Validation of a Novel Model to Discriminate Idiosyncratic Drug‐Induced Liver Injury and Autoimmune Hepatitis","year":2025,"lang":"en","type":"article","venue":"Liver International","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Mount Sinai Hospital","funders":"National Key Research and Development Program of China","keywords":"Autoimmune hepatitis; Liver injury; Drug; Medicine; Hepatitis; Drug development; Immunology; Pharmacology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003668802,0.0001401286,0.0001614803,0.0002375834,0.000159538,0.0000275953,0.0001383805,0.0001356027,0.00008394168],"category_scores_gemma":[0.00005937239,0.0001491475,0.00002899791,0.0001185337,0.00005619761,0.0001876815,0.0001775648,0.0002649092,0.00001066993],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009854504,"about_ca_system_score_gemma":0.00009094692,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001775173,"about_ca_topic_score_gemma":0.00008527451,"domain_scores_codex":[0.9990809,0.00007593466,0.0003081515,0.0002447035,0.0001450753,0.0001452546],"domain_scores_gemma":[0.9995407,0.00009151321,0.00009803525,0.00007992067,0.0001215918,0.00006825005],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007009004,0.0008469913,0.01077564,0.0003921571,0.0006499803,0.0000123675,0.01865759,0.001628374,0.6989465,0.04699806,0.0009101232,0.2194813],"study_design_scores_gemma":[0.00151561,0.00006301364,0.03716403,0.0001737968,0.0001086177,0.00001245741,0.0001622747,0.2635438,0.688242,0.0008422315,0.007849816,0.0003223357],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9887347,0.0000632557,0.006966888,0.0006948804,0.0006743112,0.0003790168,0.00005295046,0.00003207269,0.002401931],"genre_scores_gemma":[0.9923429,0.0001221667,0.004850329,0.0007263615,0.00003483788,0.00007756356,0.00002307586,0.000008277622,0.001814495],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2619154,"threshold_uncertainty_score":0.608206,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1153858083153461,"score_gpt":0.3977545619953591,"score_spread":0.282368753680013,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}