{"id":"W4406515310","doi":"10.1038/s41467-025-56041-3","title":"A multiprotein regulatory module, MED16–MBR1&2, controls MED25 homeostasis during jasmonate signaling","year":2025,"lang":"en","type":"article","venue":"Nature Communications","topic":"Calcium signaling and nucleotide metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics and Developmental Biology, Chinese Academy of Sciences; Chinese Academy of Sciences; Institute of Genetics; National Natural Science Foundation of China","keywords":"Jasmonate; Cell biology; Homeostasis; Signal transduction; Chemistry; Biology; Biochemistry; Gene; Arabidopsis","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001986475,0.0005128288,0.0002744751,0.0002089604,0.000205814,0.0003436083,0.0003426351,0.0002509467,0.001184013],"category_scores_gemma":[0.0001656809,0.0002094795,0.0003196805,0.00009887928,0.0002688099,0.0002862028,0.0004257474,0.0002775939,0.0007598556],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003813277,"about_ca_system_score_gemma":0.0001428728,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002091834,"about_ca_topic_score_gemma":0.0002629536,"domain_scores_codex":[0.9998116,0.00002149937,0.00001345965,0.00008469346,0.00003128627,0.00003752018],"domain_scores_gemma":[0.9998228,0.00001588443,0.00008653816,0.00001965856,0.00001208717,0.00004306594],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007756868,0.000005587517,0.0006089684,0.00002129117,0.000003550673,0.00007187955,0.00001249333,0.00009816537,0.9980022,0.0001073655,0.00003017569,0.000960766],"study_design_scores_gemma":[0.00002031598,0.0001040017,0.01724032,0.000007088084,0.00001677025,0.0004474365,0.00003010513,0.003695189,0.9749544,0.0001161387,0.003355948,0.00001237744],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9916599,0.00118361,0.005548585,0.00004837685,0.00002772975,0.00002238207,0.000258962,0.0002686077,0.0009817516],"genre_scores_gemma":[0.9953358,0.0001988714,0.002188253,0.00002774902,0.000007767877,0.00001627042,0.0003150606,0.0000281102,0.001882222],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001184013,"threshold_uncertainty_score":0.003960907,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01198631670526386,"score_gpt":0.2854595703081938,"score_spread":0.27347325360293,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}