{"id":"W4406521806","doi":"10.1093/cid/ciaf021","title":"Concordance of Noninvasive Plasma Cell-free DNA With Invasive Diagnostics for Diagnosis of Invasive Fungal Disease","year":2025,"lang":"en","type":"article","venue":"Clinical Infectious Diseases","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Medicine; Concordance; Cell-free fetal DNA; Disease; Plasma cell; DNA; Pathology; Computational biology; Internal medicine; Genetics; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001245997,0.000278504,0.0005709575,0.00008202132,0.0000910653,0.00002190646,0.000386218,0.0001683734,0.00001296978],"category_scores_gemma":[0.01253121,0.0002631685,0.0004154937,0.000194269,0.0006370499,0.000008018194,0.0003109158,0.0001071145,0.000001831517],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003604795,"about_ca_system_score_gemma":0.001813185,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003568143,"about_ca_topic_score_gemma":0.0005779559,"domain_scores_codex":[0.9981709,0.00008920187,0.0007388249,0.0005643418,0.0001475874,0.0002891356],"domain_scores_gemma":[0.9932757,0.004495941,0.0004935341,0.0007954273,0.000642462,0.0002969414],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0009413994,0.001608994,0.9693636,0.0007211627,0.0003789963,0.00002050287,0.00001850335,0.0005223029,0.0009495548,0.0007286111,0.02372397,0.001022346],"study_design_scores_gemma":[0.01593101,0.008223185,0.4840292,0.001113314,0.002604267,0.000003534907,0.0002642166,0.00005716115,0.4706207,0.006215929,0.009861383,0.001076135],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9906127,0.003299669,0.0008271527,0.0001617577,0.0005034118,0.000970643,0.003032084,0.00001703053,0.0005755136],"genre_scores_gemma":[0.9869179,0.01104034,0.0001389179,0.0007335197,0.0002702684,0.0005096628,0.0002620454,0.00003637765,0.00009094368],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4853345,"threshold_uncertainty_score":0.9999821,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01276039532545798,"score_gpt":0.289132308615189,"score_spread":0.276371913289731,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}