{"id":"W4406521806","doi":"10.1093/cid/ciaf021","title":"Concordance of Noninvasive Plasma Cell-free DNA With Invasive Diagnostics for Diagnosis of Invasive Fungal Disease","year":2025,"lang":"en","type":"article","venue":"Clinical Infectious Diseases","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Medicine; Concordance; Cell-free fetal DNA; Disease; Plasma cell; DNA; Pathology; Computational biology; Internal medicine; Genetics; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004436928,0.0003501165,0.000481883,0.0009817147,0.0002542999,0.00110637,0.0006429064,0.0005789023,0.001656038],"category_scores_gemma":[0.02029453,0.0003104364,0.0003758126,0.0005035292,0.0005719049,0.0006373837,0.0007024408,0.0005917411,0.000507737],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002812548,"about_ca_system_score_gemma":0.0003054977,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005881526,"about_ca_topic_score_gemma":0.0005916793,"domain_scores_codex":[0.9944812,0.00148794,0.0008032417,0.001052524,0.001773308,0.0004018743],"domain_scores_gemma":[0.9780621,0.009671615,0.007369637,0.001712944,0.002372159,0.0008115025],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001881884,0.00001525557,0.997378,0.00001488953,0.00002406683,0.0001066865,0.000070933,0.00006328942,0.0006976026,0.00001385827,0.00002865208,0.001398545],"study_design_scores_gemma":[0.00001723404,0.0005829583,0.9914976,0.00003254089,0.00006942446,0.002985375,0.0002483745,0.001358648,0.002766481,0.00006942089,0.0003587147,0.00001323024],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974725,0.0003994515,0.001006604,0.00002905369,0.00001638898,0.00002364572,0.000225476,0.00001253654,0.0008142494],"genre_scores_gemma":[0.9994191,0.00003768041,0.0003139886,0.00001251628,0.00000920544,0.000007964502,0.000154774,0.000003071825,0.00004173634],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004436928,"threshold_uncertainty_score":0.02346498,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01276039532545798,"score_gpt":0.289132308615189,"score_spread":0.276371913289731,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}