{"id":"W4406536713","doi":"10.1002/gepi.22612","title":"A Novel Statistical Method for Unmasking Sex‐Specific Genomics Signatures in Complex Traits","year":2025,"lang":"en","type":"article","venue":"Genetic Epidemiology","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Children's Hospital; University of Calgary; Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Computational biology; Biology; Genomics; Evolutionary biology; Genetics; Genome; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006586735,0.0009527031,0.001555951,0.002967678,0.0007833436,0.001570589,0.001622012,0.00121842,0.008203689],"category_scores_gemma":[0.03074493,0.0005219576,0.0027994,0.002495366,0.0008346559,0.001024678,0.001685755,0.001721704,0.002315033],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000349076,"about_ca_system_score_gemma":0.001467282,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002137064,"about_ca_topic_score_gemma":0.002550057,"domain_scores_codex":[0.997107,0.001126825,0.0002179598,0.0008824152,0.0005331896,0.0001326357],"domain_scores_gemma":[0.9860271,0.009868713,0.0007675455,0.002207301,0.0008568511,0.0002724383],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.001288882,0.0002384172,0.04824552,0.001067969,0.002800794,0.001037223,0.0006754617,0.03085743,0.03676059,0.02862483,0.04017418,0.8082288],"study_design_scores_gemma":[0.0003701754,0.0006636541,0.04011195,0.0002055126,0.0009269424,0.00342543,0.000255083,0.7638443,0.01951736,0.09494269,0.07547394,0.0002630141],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.008535885,0.0003144589,0.9842488,0.0001356129,0.0001044563,0.0001080191,0.001679966,0.004465405,0.0004072876],"genre_scores_gemma":[0.1754372,0.0004675661,0.8059688,0.0005517727,0.0003809245,0.001267827,0.010256,0.002869742,0.002800274],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.008203689,"threshold_uncertainty_score":0.03483438,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05287249980145674,"score_gpt":0.3664760927984859,"score_spread":0.3136035929970291,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}