{"id":"W4406542819","doi":"10.1136/flgastro-2024-102830","title":"Landscape of anti-IL-23 therapy in inflammatory bowel disease: recent advances","year":2025,"lang":"en","type":"article","venue":"Frontline Gastroenterology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"Medicine; Inflammatory bowel disease; Disease; Intensive care medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001703754,0.0005274118,0.001089717,0.0009826032,0.0002456021,0.001542861,0.0005854021,0.001045467,0.004721487],"category_scores_gemma":[0.002106832,0.000167817,0.0005154501,0.0008888185,0.0005232816,0.001692767,0.0008224773,0.001995899,0.001621544],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006220156,"about_ca_system_score_gemma":0.001200288,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003217499,"about_ca_topic_score_gemma":0.0008567469,"domain_scores_codex":[0.9995089,0.0001663542,0.00006493143,0.00006475,0.000140942,0.0000541595],"domain_scores_gemma":[0.9986395,0.000773013,0.0001565337,0.0000328732,0.0002885905,0.0001094809],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000429184,0.00008481646,0.0003822367,0.01233682,0.0001125229,0.0002862537,0.00009096112,0.0003871293,0.002428476,0.007512116,0.02595579,0.9499937],"study_design_scores_gemma":[0.0000615618,0.0005422497,0.0009802117,0.004802443,0.00021394,0.001087658,0.0001150031,0.000225344,0.0009838773,0.005175737,0.9857864,0.00002550927],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003124414,0.9958687,0.0002287484,0.002219524,0.0004108902,0.00000560031,0.00002306112,0.00001277567,0.000918283],"genre_scores_gemma":[0.003539634,0.9927899,0.0005373693,0.001304342,0.001179852,0.00001429439,0.00005152465,0.00000555683,0.0005775093],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004721487,"threshold_uncertainty_score":0.01579499,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004248309058504589,"score_gpt":0.2342567479101334,"score_spread":0.2300084388516288,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}