{"id":"W4406542819","doi":"10.1136/flgastro-2024-102830","title":"Landscape of anti-IL-23 therapy in inflammatory bowel disease: recent advances","year":2025,"lang":"en","type":"article","venue":"Frontline Gastroenterology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"Medicine; Inflammatory bowel disease; Disease; Intensive care medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001797115,0.0002065822,0.0002313646,0.0001540997,0.0000290287,0.000007566863,0.0002851085,0.0001084149,0.00005147937],"category_scores_gemma":[0.0000744904,0.0002024099,0.0001046161,0.00006252164,0.0001373886,0.000008776248,0.0001303571,0.0001091859,0.000006565179],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001712544,"about_ca_system_score_gemma":0.0001232667,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001778657,"about_ca_topic_score_gemma":0.0001538093,"domain_scores_codex":[0.9985343,0.0001710381,0.0004289156,0.0003913429,0.0001014584,0.000372959],"domain_scores_gemma":[0.9991955,0.000008264229,0.0001372186,0.0004576932,0.0001015549,0.00009978353],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003590561,0.0002042639,0.9785767,0.0000639818,0.00007649631,0.00005428882,0.00001407674,0.0007640129,0.01240483,0.00004588188,0.002954871,0.001250004],"study_design_scores_gemma":[0.002819784,0.000249702,0.9646521,0.00003283385,0.0000178723,0.000001965736,0.00003001107,0.0001717867,0.001632315,0.00009935424,0.03018701,0.0001052765],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945271,0.003483379,0.0005291062,0.0004729042,0.0003728004,0.0002901783,0.00008086608,0.00001735325,0.0002263029],"genre_scores_gemma":[0.9939843,0.004310594,0.0001900475,0.0008470175,0.0001237808,0.00006742181,0.0002580352,0.00002086463,0.000197954],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02723214,"threshold_uncertainty_score":0.8254034,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004248309058504589,"score_gpt":0.2342567479101334,"score_spread":0.2300084388516288,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}